2025 NFL Best Bets - Odds to Win Super Bowl LX
The No. 1 seed in the NFC and the Super Bowl betting odds favorite, the Seattle Seahawks begin their quest with a Divisional Round contest against division rival San Francisco this week. The top seeds usually have an advantage with their first round bye and that appears to be the case for Seattle. The 49ers upset Philadelphia on the road but lost a huge piece of their offense with George Kittle shelved by an Achilles injury. Seattle will also look to avoid the fate of last season’s No. 1 seed in the conference. Detroit earned the top spot but got steamrolled by Jayden Daniels and Washington in the Divisional Round. Seattle is the biggest favorite on the Divisional Round board spotting the Niners 7.5 points.
Their strong finish to the regular season moved Seattle into position as NFL futures odds favorite. The Seahawks won their last seven games and 11 of 12, including a 13-3 triumph over the Niners in the regular season finale in a game that determined the division champ and top seed. Seattle’s defense topped the NFL in fewest points allowed per game and was sixth in yards allowed. Seattle is followed closely on the futures odds board by division rival the Los Angeles Rams with Buffalo and New England representing the AFC as the teams with the next shortest odds.
Buffalo won a road playoff game for the first time in a number of years beating Jacksonville in a Wild Card contest. MVP Josh Allen accounted for three TDs sending the Bills to a showdown with No. 1 seed Denver in a rematch from last postseason. The Bills have to feel good about not seeing Kansas City in the playoff field. Buffalo was eliminated by Patrick Mahomes and the Chiefs in four of the previous five postseasons. New England will host Houston in battle of top defenses. Neither team allowed a touchdown last week and combined to give up just 382 total yards.
NFL Futures Odds
Odds to Win Super Bowl LX
| ODDS TO WIN SUPER BOWL LX |
| Buffalo Bills +525 |
Chicago Bears +1650 |
Denver Broncos +760 |
| Houston Texans +845 |
Los Angeles Rams +313 |
New England Patriots +620 |
| San Francisco 49ers +1900 |
Seattle Seahawks +286 |
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*Odds as of Tuesday, January 13, 11:00 AM ET
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Seattle Seahawks
The defense is top-notch and the offense hasn’t been too shabby either. Seattle is probably the best all-around team in the field, which is why they are positioned as the betting favorite. Sam Darnold threw for more than 4,000 yards with 25 TDs and the Seahawks averaged the third-most points in the NFL.
Los Angeles Rams
The Rams were tops on this lest for a few weeks toward the end of the regular season before consecutive losses to Seattle and Atlanta dropped them a notch. The defense began to crack late in the year but thanks to Matthew Stafford the Rams were able to outscore opponents. With Stafford tossing a NFL best 46 TD passes, the Rams were the only team to average more than 30 points per game.
Buffalo Bills
With Kansas City out of the playoff picture the Bills don’t have to worry about that threat. Buffalo was eliminated by the Chiefs in four of the last five postseasons. The run defense is shaky but Josh Allen is a special player, accounting for three TDs in the Wild Card win over Jacksonville.
New England Patriots
Every team has flaws and the Pats aren’t without theirs. They struggled offensively but the defense came up large in a Wild Card win over the Chargers. The D allowed only a field goal and limited LA to 207 yards while sacking Justin Herbert six times. They were second during the season averaging nearly 29 points and proved they can win when Drake Maye has a bad game.
Denver Broncos
No team get to the opposing QB as often as the Broncos did during the regular season. They led the NFL with 68 sacks and finished among the top 3 in total defense and scoring defense. The offense was inconsistent and managed to finish among the top half in scoring and total yards. Bo Nix threw 11 interceptions and the Broncos finished with a minus-3 turnover differential.
Houston Texans
Houston looked like the best team on Wild Card Weekend stifling the Steelers in a 30-6 victory. The game was closer than the score would indicate, though. Houston got a pair of defensive scores and tallied 23 fourth quarter points turning a one-point game into a rout. The Texans led the NFL in total defense, was second in scoring defense and their plus-17 turnover differential was also second best.
Chicago Bears
The luck has to run out at some point. The Bears executed another fourth-quarter comeback upending rival Green Bay in the Wild Card round. In his postseason debut Caleb Williams threw two TD passes and the Bears overcame an 18-point deficit for the win. It was their seventh fourth-quarter comeback win this season.
San Francisco 49ers
Taking on Seattle in the Divisional Round with yet another injured starter out of the lineup has the Niners at the bottom of the odds list. George Kittle exited last week’s game with an Achilles injury yet the team rallied to upset the defending champions. I’m not so sure they’ll have the same good fortune this week.
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