NFL Week 5 Betting Odds - NFL Lines

NFL Week 5 Betting Lines

NFL Week 5 Betting Lines

There is often plentiful discussion about the often-weak lineup of Thursday night games each NFL season. Although the NFL has improved its Thursday night product, it is still usually weaker than the rest of the card. However, for Week 5 of the 2021 season, the Thursday night matchup of the Seattle Seahawks hosting the Los Angeles Rams is hard to beat. Consider the fact that the Rams beat the host Seahawks Seattle in last year's NFC Playoffs. This year Los Angeles has a new quarterback in veteran Matthew Stafford from the Detroit Lions, where his career has largely gone to waste. Stafford will be going up against Russell Wilson, one of the most dynamic signal callers in history. Seattle showed moderate defensive improvement last year before the roof caved in on them in the playoff loss to the Rams.

NFL Week 5 Schedule & Lines

MATCHUP TIME SPREAD TOTAL
Thursday, October 7
Los Angeles Rams at Seattle Seahawks 8:20 PM TBA TBA
Sunday, October 10
New York Jets at Atlanta Falcons 1:00 PM TBA TBA
Philadelphia Eagles at Carolina Panthers 1:00 PM TBA TBA
Green Bay Packers at Cincinnati Bengals 1:00 PM TBA TBA
New England Patriots at Houston Texans 1:00 PM TBA TBA
Tennessee Titans at Jacksonville Jaguars 1:00 PM TBA TBA
Detroit Lions at Minnesota Vikings 1:00 PM TBA TBA
Denver Broncos at Pittsburgh Steelers 1:00 PM TBA TBA
Miami Dolphins at Tampa Bay Buccaneers 1:00 PM TBA TBA
New Orleans Saints at Washington 1:00 PM TBA TBA
Cleveland Browns at Los Angeles Chargers 4:05 PM TBA TBA
Chicago Bears at Las Vegas Raiders 4:05 PM TBA TBA
San Francisco 49ers at Arizona Cardinals 4:25 PM TBA TBA
New York Giants at Dallas Cowboys 4:25 PM TBA TBA
Buffalo Bills at Kansas City Chiefs 8:20 PM TBA TBA
Monday, October 11
Indianapolis Colts at Baltimore Ravens 8:15 PM TBA TBA

The Dallas Cowboys will host the New York Giants in a Sunday afternoon NFC East FOX feature. Last year the NFC "Least" failed to produce a team with a winning record. By this point in the season, we'll see if the division has improved. We'll also learn if Daniel Jones has enough help to make a real move as the Giants quarterback. And at this point, we'll also know if the Cowboys have made any real strides defensively. Dak Prescott returns to quarterback what many gamblers expect to be a resurgent Cowboys team. New York was surprisingly competitive under rookie head coach Joe Judge in 2020.

One of the week's best matchups comes from the Valley of the Sun, where the Arizona Cardinals will host the San Francisco 49ers. Arizona made significant defensive strides last year, and Kyler Murray is proving his worth at the quarterback position. San Francisco is just two seasons removed from a Super Bowl appearance in which they seemed to have the Lombardy Trophy in hand deep into the fourth quarter. Since blowing the Super Bowl to Kansas City, the 49ers have never been the same. Now comes the added intrigue of drafting Trey Lance in the first round. Lance will try to unseat often injured starter Jimmy Garoppolo.

NBC Sunday Night Football usually gets the game of the week, and that is clearly the case for Week 5 as the Kansas City Chiefs host the Buffalo Bills in a rematch of the 2020 AFC Championship Game. Buffalo quarterback Josh Allen won over a lot of skeptics last season, while Patrick Mahomes is the quarterback that every other NFL team dreams of having. Buffalo has the revenge factor and will be getting points. But Kansas City put the Bills in their place last time in a statement-making 38-24 win and payout.

Monday Night Football features a potential AFC playoff game between the Baltimore Ravens and visiting Indianapolis Colts. It also features yet another tale of two quarterbacks. Carson Wentz arrives as a refugee from the Philadelphia Eagles, where he was the favorite whipping boy of the media and fans. Wentz is to take over for Philip Rivers, who was a one-year stop-gap answer. Many NFL insiders still believe that Wentz has championship Pro Bowl potential. But he is often injured and has only one partial playoff game played on his resume. On the positive, he arrives at a much less nasty city and a more united organization.

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