NFL Week 16 Betting Online
The NFC West is touted as one of the best divisions in the NFL, and a matchup that could determine its championship will kick off Week 16 on Amazon Prime when the Seattle Seahawks host the Los Angeles Rams. Despite a 10-7 record under rookie head coach Mike Macdonald, the Seahawks failed to make the playoffs. Thus, Seattle has plenty of motivation to close the postseason sale this year and will have a new quarterback to help make it happen. Sam Darnold arrives from the Minnesota Vikings, where he was the unwanted starting QB on a 14-3 team. Veteran Matthew Stafford is back under center for the Rams, who are coming off two playoff campaigns and six in their eight seasons under head coach Sean McVay.
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2025 NFL Week 16 Schedule
Week 16 offers two Saturday games on FOX that are attractive division rivalry showdowns. The Washington Commanders will host the Philadelphia Eagles. Of course, the Eagles spanked the Commanders in last year’s NFC championship game.
And then from the NFC North, the NFL’s oldest rivalry will renew with the Chicago Bears hosting the Green Bay Packers. The Bears are facing low expectations but could have plenty of value and upside with rookie head coach and quarterback whisperer Ben Johnson, who was hired to fix quarterback Caleb Williams, the first overall pick of the 2024 NFL Draft.
In the Sunday early window, an interesting interconference matchup could have major playoff implications. The Dallas Cowboys will host the Los Angeles Chargers in what could be a critical game for both teams.
Normally, the Cowboys are overrated and fall short of the incessant hype. But this year, Dallas is facing unusually small expectations, and that may serve to tone down the perpetual Jerry World Circus that has harmed the team since head coach Jimmy Johnson left in a huff after winning two Super Bowls in 1994.
Chargers' Jim Harbaugh remains one of the most interesting characters in the game. Harbaugh has wanted back in the NFL for several years but had to rebuild his stock in the college ranks at Michigan, where he won the 2023 national championship before leaving one step ahead of the posse for a spying scandal that still taints the program. Harbaugh has a habit of wearing out his welcome wherever he goes, but also winning at every stop he makes. The Chargers are desperate to make noise in a crowded Southern California market. Harbaugh was hired to jumpstart a franchise that was not even wanted when it arrived from San Diego because of stadium issues.
The late Sunday afternoon window has an intriguing interconference matchup between two contenders. The Detroit Lions will host the Pittsburgh Steelers in a game that should have major playoff implications.
On Sunday Night, NBC will air a game that could have playoff ramifications in the AFC. The Miami Dolphins will host the Cincinnati Bengals. Miami has the talent to contend, but it all depends on quarterback Tua Tagovailoa staying healthy. And even if Tua answers the bell, the main problem at Miami is Mike McDaniel, who is the softest head coach in the NFL.
Monday Night Football on ESPN offers some intrigue with two aspiring playoff teams. The San Francisco 49ers will visit the Indianapolis Colts in a game that both teams will need. The 49ers were touted as Super Bowl material last year before injuries wiped out their campaign.
NFL Schedule
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