2025 NFL Week 18 Online Betting - Football Picks

NFL Week 18 Betting Online

NFL Week 18 Betting Odds

Week 18 will have a throwback feel, with the entire card being played on a Sunday, like it used to be before Monday Night Football was created in 1970, when the American Football League and National Football League merged. The last weekend of the regular season will likely offer some must-win games for teams who must post a victory to gain a playoff spot. On the other hand, there will be plenty of load management by teams looking to stay healthy for the 2024 NFL Playoffs. And there will be teams in a hurry to end losing seasons and hit the road for home. All games for Week 18 are on a flex schedule, meaning that starting times and TV coverage will be determined a week or so before the games. Because of the combination of virtual playoff and preseason games, Week 18 has become the most challenging handicap of all.

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2025 NFL Week 18 Schedule

MATCHUP TIME (ET) TV
Sunday, January 4
Saints at Falcons TBA TBA
Jets at Bills TBA TBA
Lions at Bears TBA TBA
Browns at Bengals TBA TBA
Chargers at Broncos TBA TBA
Colts at Texans TBA TBA
Titans at Jaguars TBA TBA
Cardinals at Rams TBA TBA
Chiefs at Raiders TBA TBA
Packers at Vikings TBA TBA
Dolphins at Patriots TBA TBA
Cowboys at Giants TBA TBA
Commanders at Eagles TBA TBA
Ravens at Steelers TBA TBA
Seahawks at 49ers TBA TBA
Panthers at Buccaneers TBA TBA
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At first glance, the Week 18 schedule is loaded with seemingly attractive division rivalry games. But will those games matter? The best example comes from the 2024 season when the Kansas City Chiefs faced the Las Vegas Raiders. With nothing on the line for the Chiefs, Kansas City rested quarterback Patrick Mahomes to protect him for the playoffs. Thus, a great rivalry matchup that fans look forward to was turned into a virtual preseason affair. This is a great example of how the expanded playoff format gives and takes for the NFL. And it is a lesson on how difficult it is to bet on the final weekend of the regular season successfully.

The Chiefs and Raiders will again close out the regular season, this time from Las Vegas, which will make for a fun road trip for Kansas City fans, even if the game doesn’t have anything on the line.

Also from the AFC West is a matchup of the Los Angeles Chargers at the Denver Broncos, where playoff position could be at stake for each side.

The Pittsburgh Steelers will host the Baltimore Ravens and could be playing for their postseason lives. What will be interesting is if Baltimore has already clinched its playoff position. This means that the Steelers would likely protect their best players from potential injury, which could open the door for their hated rivals.

Once upon a time, a matchup between the Dallas Cowboys and New York Giants was for all the marbles in the NFC East. This year, it may be for nothing as each team is facing low expectations.

Also from the NFC East is the old rivalry matchup of the Washington Commanders at the Philadelphia Eagles. Can Washington again confound the experts with a playoff berth?

The NFC North was once known as the Black and Blue division in football’s golden age. While the game and teams have changed, the historic rivalry matchups remain. The Chicago Bears will host the Detroit Lions, and the Green Bay Packers will visit the Minnesota Vikings.

In the NFC West, the Los Angeles Rams will host the Arizona Cardinals, while the San Francisco 49ers host the Seattle Seahawks. It is conceivable that all of these teams could be fighting for a playoff spot or positioning.

In the AFC East, ancient rivalries will renew with the Miami Dolphins at the New England Patriots and the New York Jets at the Buffalo Bills. Miami and cold weather have been a terrible combination, but if Buffalo has nothing to play for, that could change the handicapping dynamics.

NFL Schedule

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