2025 NFL Week 13 Best Bets - Football Lines

2025 NFL Week 13 Best Bets - Football Lines

A busy Week 13 of NFL action starts with the traditional Thanksgiving day games hosted by Detroit and Dallas, includes a “Thursday Night Football” game on Friday afternoon and concludes with a classic Super Bowl rematch on Monday Night Football. The betting week starts early on Thursday with a crucial NFC North showdown between the Green Bay Packers and Detroit Lions, one of five divisional matchups on the slate. Both teams are one win behind the Bears in congested division standings and the Lions have one more loss leaving them currently outside the NFC playoff picture.

And speaking of the Bears they put their first place standing and 4-game winning streak on the line in Friday’s showdown with the NFC East leading Eagles. Philly blew a 21-point lead in Sunday’s loss to Dallas leaving them tied for the second best record in the NFC. With a glimmer of postseason hope the Cowboys entertain Kansas City on Thursday afternoon. The Chiefs may have saved their season with a come from behind 23-20 overtime win over the Colts on Sunday. The football smorgasbord ends with an AFC North bout between Cincinnati and Baltimore. Winners of five straight the Ravens caught Pittsburgh at the top of the division standings. And the Bengals are hoping to have Joe Burrow back to spark their own late season surge.

There are no byes this week so all 32 teams are in action. The week concludes with the 13th all-time meeting between the New York Giants and New England Patriots. Two of the previous 12 games took place in the Super Bowl four years apart with the Giants prevailing both times. In one of the biggest Super Bowl upsets the G-Men ended the Pats’ quest for a perfect season with a 17-14 win in Super Bowl XLII. New England won all 16 regular season games and waltzed by Jacksonville and San Diego in the playoffs, but they were denied making history.

NFL Betting Lines

2025 NFL Week 13 Betting Lines

*Odds as of Wednesday, November 26, 11:00 AM ET

Similar to last week three games boast opening double-digit point spreads. Winners of six in a row and with MVP candidate Matthew Stafford playing marvelous football, the Rams hit the board as a 10.5-point road favorite against Carolina. Stafford threw three TD passes in Sunday’s 34-7 win over Tampa Bay and leads the NFL with 30 scoring strikes. During the current winning streak Stafford has 22 TD passes without being intercepted. He’s thrown just two picks all season the last coming in Week 3. LA covered the 14.5-point spread beating New Orleans 34-10 in Week 9.

Another NFC West team is laying 10.5-points on the early line, but the Seahawks are home for their contest with Minnesota. And the line elevated with Vikings’ QB J.J. McCarthy in concussion protocol. If McCarthy is unable to play Max Brosmer would get the nod. Sam Darnold led the Vikings to 14 wins a season ago and was not re-signed, allowing him to join the Seahawks as a free agent. Darnold leads the NFL averaging 9.3 yards per pass attempt with 19 TDs.

Coming off their bye the Chargers get a chance to put that 35-6 shellacking by Jacksonville in Week 11 behind them. And they have the patsy coming to town in order to do that. The Bolts opened at -10 for their AFC West contest with the hapless Raiders. Vegas has lost five straight and nine of 10 since a season-opening victory at New England. They’ve been terrible offensively scoring 10 points or less five times, including in Sunday’s 24-10 loss to Cleveland. They are 2-7-1 ATS in their last 10 games.

All three double-digit dogs stayed within the point spread last week earning payouts, and they are 6-0 ATS in the last six games. Carolina was the last team getting at least 10 points to win a game outright knocking off Green Bay, 16-13, in Week 9 when catching 13.5 points.

NFL Schedule

• Week 1
• Week 2
• Week 3
• Week 4
• Week 5
• Week 6
• Week 7
• Week 8
• Week 9
• Week 10
• Week 11
• Week 12
• Week 13
• Week 14
• Week 15
• Week 16
• Week 17
• Week 18

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