2018 College Football Week 1 Betting - NCAA Football Spreads

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2018 College Football Week 1 Betting Odds

With an emphasis on quality wins in the college football playoff era, we’ve seen some enticing season-opening matchups in the past. And we get a few more to kickoff the 2018 season. Defending champion Alabama takes on Louisville in a game that would be far more interesting if Lamar Jackson were still around. The early line has Bama as a 25.5-point favorite and its time to see if the Cardinals can compete with elite competition now that Jackson has departed. Other SEC teams are featured in several big games as well.

LSU and Miami tee it up in Arlington with the schools facing each other for the first time since 2005 and just the second time in 30 years. Avoiding a Week 1 patsy, the Washington Huskies step out of their comfort zone to face Auburn in the Chick-fil-A Kickoff game, the first Pac-12 team to participate in the event. A battle between two of the top quarterbacks in the country could unfurl with UW’s Jake Browning and the Tigers Jarrett Stidham.

2018 NCAA Football Week 1 Betting Schedule

August 23, 2018 to September 3, 2018

Central Florida at Connecticut ( +24.5 )

Northwestern at Purdue ( -3 )

Week one’s best matchup for Thursday night is a pair of dark horse teams looking to surprise in the Big Ten West Division. The Purdue Boilermakers are back! In just one season on the job head coach Jeff Brohm gave this slumping program its belief again. Purdue was tough, smart and productive en route to a surprise 7-6 record capped off with a Foster Farms Bowl win last year. The Northwestern Wildcats are coming off their second ten-win season in three years as they finished 10-3 and as Music City Bowl champs. Head coach Pat Fitzgerald has led this program to its greatest heights since he was a linebacker on the 1995 Rose Bowl team. More

Wake Forest at Tulane ( +7 )

As college football fanatics celebrate Week One’s Thursday night opening of the regular season there is an intriguing handicap of an Atlantic Coast Conference over achiever against a Group of Five team stuck in the muck but hosting what for them is a big home opener against a Power Five school. The Tulane Green Wave have made one bowl game since 2002 but will get their shot for national attention against the visiting Wake Forest Demon Deacons. Wake Forest is coming off their second straight bowl season and has shown methodical improvement since reaching rock bottom in 2013. More

Utah State at Michigan State ( -25 )

Syracuse at Western Michigan ( +6 )

Week one action includes the unique situation of a Power Five school traveling to play on the road on the home field of a Group off Five program. While this is a rare occurrence the Syracuse Orange will make the trip to Kalamazoo, Michigan to face the Western Michigan Broncos. Syracuse is again picked for the basement of the Atlantic Coast Conference Atlantic division as third year head coach Dino Babers is yet to break through. Western Michigan is no longer “Rowing the Boat” and took a big step back last year following the departure of PJ Fleck for the riches of the Big Ten and Minnesota. More

Western Kentucky at Wisconsin ( -34.5 )

Friday night action for Week One includes a team that continues to garner respect and betting activity and the highest expectations in the history of their program. The Wisconsin Badgers were one touchdown shy of making the College Football Playoff last December and have almost all of their offense back including all five starters from what is considered to be the best offensive line in the country. For the Western Kentucky Hilltoppers an opening game at Madtown may pay a lot of bills but at the cost of a lot of bruises both physically and emotionally. More

Colorado State vs. Colorado ( -6 )

San Diego State at Stanford ( -14.5 )

The Stanford Cardinal has been the class of the Pac-12 North since the league expanded, and the expectation remains the same heading into 2018. With another legitimate Heisman Trophy candidate in Bryce Love leading the offense, the Cardinal is looking for its fifth division title in eight years. But they better not overlook the San Diego State Aztecs, who won last year’s meeting and should contend for the Mountain West title. The West Coast powers kick off Week 1 on Friday night. More

Army at Duke ( -10.5 )

Among the most attractive Friday night openers for Week One is the matchup between the Duke Blue Devils and the visiting Army Black Knights. These are two college football programs regarded for winning despite respectively strong academic requirements at their schools which are also nothing close to being football factories. Despite that both teams have enjoyed recent success and appear to be set to sustain it for 2018. Yet their matchup is also one of opposites as far as offensive styles and ability. More

Florida Atlantic at Oklahoma ( -21 )

All aboard the Lane Train! Lane Kiffin’s first year in Boca Raton as the head coach of the Florida Atlantic Owls was a smashing success. After a 1-3 start that included a head scratcher of a loss to Buffalo, the Owls ran the table in Conference USA play. They crushed North Texas for the Conference USA Championship, and they followed that up by blasting Akron 50-3 in the Boca Raton Bowl. FAU has one of the longest winning streaks in the country, and the Owls have a chance to make some serious noise against the Oklahoma Sooners in Week 1 of the college football season. More

Houston at Rice ( +25.5 )

Oregon State at Ohio State ( -37.5 )

Week One gives all of us a brief respite from all of the recent off the field issues that have dominated training camp news. At least one would think. But when it comes to Saturday’s game at Columbus between the Oregon State Beavers and Ohio State Buckeyes the story line will be primarily focused on the one man that will be absent from the field. Ohio State head coach Urban Meyer is out due to suspension. Fortunately for the loaded Buckeyes it will likely not matter against a vastly undermanned Oregon State team. The only question is if the Bucks will be sharp enough to cover the big spread without their head coach. More

Appalachian State at Penn State ( -23.5 )

No fan of the Appalachian State Mountaineers will ever forget the team’s first game on the Big Ten Network. At the time, Appalachian State was an FCS team, but the Mountaineers soon launched themselves into the national consciousness. The Mountaineers pulled off one of the most stunning upsets ever when they beat No. 5 Michigan 34-32 in Ann Arbor. It set the program on a crash course with the FBS, where it has been one of the best Group of Five teams since moving up to the FBS five years ago. Appalachian State is again opening its season on the Big Ten Network, and the Penn State Nittany Lions are looking to avoid what would be a disastrous Week 1 upset. More

Akron at Nebraska ( -23 )

Among the most highly anticipated Week One matchups for Saturday is the Nebraska Cornhuskers hosting the Akron Zips. Indeed, Nebraska fans have been counting down the days for this epic evening as Scott Frost will be coaching in his first game for the Big Red. Frost arrives after his sensational work at Central Florida in which he led the Knights to an undefeated season and bowl win over Auburn. Frost is a native of Nebraska and quarterbacked the Huskers to their last national championship in 1997. In Akron the Huskers face a manageable opponent that barely made a minor bowl game last year. More

Massachusetts at Boston College ( -18 )

Kent State at Illinois ( -16 )

Texas State at Rutgers ( -16.5 )

Indiana at Florida International ( +10.5 )

Northern Illinois at Iowa ( -12 )

The last time the Iowa Hawkeyes hosted the Northern Illinois Huskies, it was the beginning of another fantastic season for Northern Illinois. The Huskies were coming off an undefeated regular season and an Orange Bowl appearance, and they were aiming to repeat the feat. Northern Illinois upset Iowa as an underdog per the CFB odds, and the Huskies went on to finish the regular season undefeated once more. The Huskies are a popular upset pick in Week 1 of the 2018 season, and they will look to reward bettors once more. More

Texas vs. Maryland (+11 )

The Maryland Terrapins cannot wait to start the regular season. To say it’s been a tumultuous offseason for head coach DJ Durkin and the Terps is an understatement. Durkin has been under heavy criticism due to a number of actions and allegations. In late May, offensive lineman Jordan McNair collapsed during an offseason workout and died two weeks later. McNair’s tragic death led to some digging into the program and two weeks ago, there were reports that Durkin had fostered a toxic environment within the locker room. That has led to even more allegations of wrongdoing on the side of Durkin, and there is a chance that he might be fired for cause before the start of Week 1 of the college football season. The Texas Longhorns will look to take advantage of the turmoil surrounding Maryland this Saturday. More

Boise State at Troy ( +10.5 )

Marshall at Miami Ohio ( -3 )

SMU at North Texas ( -3.5 )

Middle Tennessee State at Vanderbilt ( -4.5 )

BYU at Arizona ( -13 )

As quickly as Rich Rodriguez turned the Arizona Wildcats around, the program went into a funk and RichRod was let go. It was an up and down tenure for the former coach, who won 26 games his first three seasons and posted the team’s first double-digit win campaign in 16 seasons with 10 in 2014. However, three victories in 2016 was the beginning of the end and Rodriguez was jettisoned amid a scandal following the 2017 season. The Wildcats made a good hire in Kevin Sumlin, who opens a new chapter in Arizona football in Week 1 against the BYU Cougars. More

Texas San Antonio at Arizona State ( -17 )

UNLV at USC ( -26 )

Cincinnati at UCLA ( -16 )

Washington vs. Auburn ( -2.5 )

The premier game of Week 1 of the college football season will take place in Atlanta on Saturday afternoon when the Washington Huskies face the Auburn Tigers. For Washington, the pride of the program and the PAC 12 as a whole is at stake, with some going so far as to say that the PAC 12 won’t be able to get a one-loss champion in the College Football Playoff if the Huskies don’t win this game. Meanwhile, Auburn is looking to shake off a disappointing end to the season that saw the Tigers drop games to Georgia and UCF even though they were able to knock off arch-rivals Georgia and Alabama in the regular season. More

Central Michigan at Kentucky ( -17 )

Mark Stoops has continued to slowly lead the Kentucky Wildcats in the right direction. The longest-tenured head coach in the SEC East has rebuilt this program from the ground up, and Kentucky is looking to make it to a bowl game for the third straight season in 2018. The Wildcats will face a somewhat tough opponent in their Week 1 opener though, when the Central Michigan Chippewas come to town. Central Michigan went 8-5 last season and knocked off a Power Five opponent in non-conference play. Kentucky is trying to avoid a similar fate. More

Mississippi at Texas Tech ( -1.5 )

Who’s ready for a good old-fashioned shootout? That’s what you should expect when the Mississippi Rebels and Texas Tech Red Raiders square off in Week 1 action. Texas Tech is in a make or break season with Kliff Kingsbury. Kingsbury started off strong in his first year in Lubbock, posting an 8-5 record, but he has failed to win more than seven games in a season since that point. Fans and the administration are growing restless with their former star quarterback, and another middling year might be Kingsbury’s last. More

Coastal Carolina at South Carolina ( -29.5 )

West Virginia at Tennessee ( +9.5 )

Dana Holgorsen has been seen as one of the sharpest offensive minds in college football over the last two decades. Holgorsen is an innovator who isn’t afraid to try new things in order to get results, and that has helped him succeed in the wide-open Big 12 during his time as head coach of the West Virginia Mountaineers. He and West Virginia will look to start off right in Week 1 of the 2018 season with a win over the Tennessee Volunteers. More

North Carolina at California ( -5 )

The California Golden Bears started the Justin Wilcox era on the right foot. Wilcox’s first game as head coach of the Golden Bears last year was a win over these North Carolina Tar Heels. California was a sizeable 13.5-point underdog in the game per the CFB betting odds, but Ross Bowers proved to be too much for this secondary. UNC would love to return the favorite and get an important non-conference road victory in Week 1 of the 2018 campaign. More

Bowling Green at Oregon ( -28.5 )

Old Dominion at Liberty ( +6 )

Michigan at Notre Dame ( +2.5 )

If an alien arrived from outer space and asked what college football is all about there is a Week One matchup that would easily define it. Tradition, history, and potential excellence on the gridiron from two strong academic institutions that strive to “do it the right way” are all there for Saturday’s Marquee Matchup of the Michigan Wolverines and Notre Dame Fighting Irish. This showdown of historic power brands will take place under the watchful eye of Touchdown Jesus himself at Notre Dame Stadium, one of the grandest venues of this or any sport. And to top off all of that both teams have the ability to make a deep run towards the post season this year. More

Louisville at Alabama ( -25.5 )

With Week One finally here the top ranked Alabama Crimson Tide will be going for their sixth national championship since 2009 under head coach Nick Saban, who must be regarded as the greatest college football coach of all time. Saban has been coy about who will be his starting quarterback but regardless of whether its Jalen Hurts or Tua Tagovailoa the Tide is expected to romp towards a playoff berth at bare minimum. Meanwhile the Louisville Cardinals are moving on as Heisman Trophy winning quarterback Lamar Jackson is now in the NFL. Petrino faces even bigger challenges in replacing nine defensive starters. More

Miami vs. LSU ( +2.5 )

Without question one of the most highly anticipated Week One matchups is set for Sunday night when the Miami Hurricanes travel to Heart of Texas to face the LSU Tigers in the only game for Sunday. The Dallas Cowboys AT&T Stadium will host the matchup. This primetime showdown of two ranked teams will have the entire country focused on it. For Miami it’s a chance to maintain the momentum started last year in their first season under head coach Mark Richt. For LSU it’s a chance to cool off the hot seat talk in regards to lightly regarded coach Ed Orgeron. More

Virginia Tech at Florida State ( -6 )

On Monday night Week One will wrap up with an outstanding matchup of ranked Atlantic Coast Conference teams as the Florida State Seminoles will host the Virginia Tech Hokies. The game marks the debut of new Florida State head coach Willie Taggart who arrives after the ugly departure of Jimbo Fisher to the riches of Texas A&M. The Seminoles were sluggish at the finish of 2017 as everyone knew that Fisher wanted out of town. FSU’s 7-6 finish capped off a stunning fall from the national championship of 2013. For Virginia Tech they are trying to build upon a new foundation under third year coach Justin Fuente who arrived with much fanfare and has posted 10 and nine-win seasons while stepping up recruiting. More

Week 1 College Football Games of the Week

Michigan at Notre Dame, Saturday, September 1, 7:30 p.m. ET (NBC)

The time is now for Jim Harbaugh to deliver. Entering his fourth season the Wolverines have been decent, but not good enough to reach the playoff or win the Big Ten. Michigan won 10 games in each of his first two seasons and slipped to 8-5 last year. It’s hard to imagine his seat being hot, but it is getting warm. The Wolverines have failed to land a signature win in Harbaugh’s tenure, but this is a chance right out of the chute to get that out of the way and move on to a possible title.

This matchup was a fixture on the schedule from 1978 to 2014 with the teams playing 30 times in that span. The teams haven’t met since Notre Dame’s 31-0 blowout win, which was one of the nails in Brady Hoke’s coffin. Harbaugh took over the following season and got the Wolverines back to respectability, but this is one that will mean more to the coach than any other. Big Blue will also have the services of former Ole Miss quarterback Shea Patterson, who was given the green light to play following his transfer.

Louisville vs. Alabama, Saturday, September 1, 8 p.m. ET (ABC)

The Tide hasn’t lost a regular season nonconference game since Nick Saban’s first season in 2007, and that isn’t going to change in this one. Alabama is loaded, despite having 12 players selected in the NFL draft, and they are a good bet to return to the College Football Playoff.

Louisville’s run in the ACC may appear to be over following the departure of Jackson, who was the team’s offense during his stay. Holes exist on the offense with an unproven quarterback, but that’s the least of Bobby Petrino’s concerns. The defense staggered last year and there’s a new coordinator in 2018. And the Cards return just two starters on that side of the football. Louisville opened as a huge underdog and it would be considered a moral victory if they hung within a few scores.

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NCAA Football Top Teams

Alabama Clemson Georgia Ohio State Oklahoma
Miami Auburn Wisconsin Notre Dame Penn State
Washington USC LSU Stanford Virginia Tech
Michigan State Michigan TCU Florida State Oklahoma State
UCF Texas South Carolina Memphis Texas A&M

2018 NCAA Football Weekly Schedule

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Live Lines

  • Time
  • Teams
  • Spread
  • Total
  • Odds
  • Ago 01

    6:00 AM

    • 10631
    • Devin White
    • +702
    • 10632
    • Nick Bosa
    • +727
    • 10633
    • Quinnen Williams
    • +782
    • 10634
    • Devin Bush
    • +752
    • 10635
    • Ed Oliver
    • +1508
    • 10636
    • Josh Allen
    • +1508
    • 10637
    • Clelin Ferrell
    • +2014
    • 10638
    • Brian Burns
    • +2014
    • 10639
    • Montez Sweat
    • +1508
    • 10640
    • Rashan Gary
    • +2216
    • 10641
    • Jahlani Taval
    • +2014
    • 10642
    • Andraez Williams
    • +2521
    • 10643
    • Jerry Tillery
    • +3030
    • 10644
    • Darnell Savage
    • +2350
    • 10645
    • Jonathan Abram
    • +3540
    • 10646
    • Christian Wilkins
    • +3540
    • 10647
    • Taylor Rapp
    • +3540
    • 10648
    • Deandre Baker
    • +3540
    • 10649
    • Deionte Thompson
    • +4000
    • 10650
    • Nasir Adderley
    • +4500
    • 10651
    • Marquise Blair
    • +4000
    • 10652
    • Juan Thornhill
    • +4000
    • 10653
    • Jachal Polite
    • +4500
    • 10654
    • Byron Murphy
    • +4500
    • 10655
    • Rock Ya-Sin
    • +3540
    • 10656
    • Dexter Lawrence
    • +5000
    • 10657
    • L.J Collier
    • +5000
    • 10658
    • Joejuan Williams
    • +5000
    • 10659
    • Justin Layne
    • +5000
  • Ago 01

    6:00 AM

    • 10601
    • Kyler Murray
    • +196
    • 10602
    • Josh Jacobs
    • +855
    • 10603
    • Mecole Hardman
    • +1480
    • 10604
    • N Keal Harry
    • +1718
    • 10605
    • Drew Lock
    • +2506
    • 10606
    • Daniel Jones
    • +2622
    • 10607
    • David Montgomery
    • +1611
    • 10608
    • AJ Brown
    • +2506
    • 10609
    • Terry McLaurin
    • +4500
    • 10611
    • Darrell Henderson
    • +2633
    • 10612
    • Will Grier
    • +5000
    • 10613
    • Andy Isabella
    • +3598
    • 10614
    • Dwayne Haskins
    • +783
    • 10615
    • Marquise Brown
    • +2154
    • 10616
    • TJ Hockenson
    • +2154
    • 10617
    • Miles Sanders
    • +1922
    • 10618
    • Noah Fant
    • +2506
    • 10619
    • Deebo Samuel
    • +2154
    • 10620
    • Parris Campbell
    • +2742
    • 10621
    • DK Metcalf
    • +3105
    • 10622
    • JJ Arcega-Whiteside
    • +3727
    • 10624
    • Hakeem Butler
    • +3983
    • 10625
    • Damien Harris
    • +5000
    • 10626
    • Irv Smith
    • +5000
  • Oct 05

    12:00 PM

    • 10001
    • Arizona Cardinals
    • +15000
    • 10002
    • Atlanta Falcons
    • +3593
    • 10003
    • Baltimore Ravens
    • +5700
    • 10004
    • Buffalo Bills
    • +9000
    • 10005
    • Carolina Panthers
    • +5500
    • 10006
    • Chicago Bears
    • +1650
    • 10007
    • Cincinnati Bengals
    • +17500
    • 10008
    • Cleveland Browns
    • +1400
    • 10009
    • Dallas Cowboys
    • +2650
    • 10010
    • Denver Broncos
    • +9000
    • 10011
    • Detroit Lions
    • +11000
    • 10012
    • Green Bay Packers
    • +1800
    • 10013
    • Houston Texans
    • +4800
    • 10014
    • Indianapolis Colts
    • +985
    • 10015
    • Jacksonville Jaguars
    • +4500
    • 10016
    • Kansas City Chiefs
    • +740
    • 10017
    • Los Angeles Chargers
    • +1400
    • 10018
    • Los Angeles Rams
    • +1250
    • 10019
    • Miami Dolphins
    • +32500
    • 10020
    • Minnesota Vikings
    • +2800
    • 10021
    • New England Patriots
    • +690
    • 10022
    • New Orleans Saints
    • +925
    • 10023
    • New York Giants
    • +10500
    • 10024
    • New York Jets
    • +9000
    • 10025
    • Oakland Raiders
    • +8500
    • 10026
    • Philadelphia Eagles
    • +1525
    • 10027
    • Pittsburgh Steelers
    • +2300
    • 10028
    • San Francisco 49ers
    • +3750
    • 10029
    • Seattle Seahawks
    • +2650
    • 10030
    • Tampa Bay Buccaneers
    • +7953
    • 10031
    • Tennessee Titans
    • +7000
    • 10032
    • Washington Redskins
    • +11500
  • Oct 05

    12:00 PM

    • 10101
    • Baltimore Ravens
    • +2550
    • 10102
    • Buffalo Bills
    • +4500
    • 10103
    • Cincinnati Bengals
    • +8000
    • 10104
    • Cleveland Browns
    • +695
    • 10105
    • Denver Broncos
    • +4300
    • 10106
    • Houston Texans
    • +2550
    • 10107
    • Indianapolis Colts
    • +490
    • 10108
    • Jacksonville Jaguars
    • +2200
    • 10109
    • Kansas City Chiefs
    • +370
    • 10110
    • Los Angeles Chargers
    • +690
    • 10111
    • Miami Dolphins
    • +16000
    • 10112
    • New England Patriots
    • +345
    • 10113
    • New York Jets
    • +4500
    • 10114
    • Oakland Raiders
    • +3950
    • 10115
    • Pittsburgh Steelers
    • +1135
    • 10116
    • Tennessee Titans
    • +3400
  • Oct 05

    12:00 PM

    • 10121
    • Arizona Cardinals
    • +7200
    • 10122
    • Atlanta Falcons
    • +1469
    • 10123
    • Carolina Panthers
    • +2526
    • 10124
    • Chicago Bears
    • +765
    • 10125
    • Dallas Cowboys
    • +1200
    • 10126
    • Detroit Lions
    • +4800
    • 10127
    • Green Bay Packers
    • +845
    • 10128
    • Los Angeles Rams
    • +575
    • 10129
    • Minnesota Vikings
    • +1325
    • 10130
    • New Orleans Saints
    • +350
    • 10131
    • New York Giants
    • +5500
    • 10132
    • Philadelphia Eagles
    • +685
    • 10133
    • San Francisco 49ers
    • +1675
    • 10134
    • Seattle Seahawks
    • +1150
    • 10135
    • Tampa Bay Buccaneers
    • +4350
    • 10136
    • Washington Redskins
    • +5300
  • Oct 05

    12:00 PM

    • 10201
    • Buffalo Bills
    • +1050
    • 10202
    • Miami Dolphins
    • +5500
    • 10203
    • New England Patriots
    • -475
    • 10204
    • New York Jets
    • +555
  • Oct 05

    12:00 PM

    • 10205
    • Baltimore Ravens
    • +325
    • 10206
    • Cincinnati Bengals
    • +1850
    • 10207
    • Cleveland Browns
    • +133
    • 10208
    • Pittsburgh Steelers
    • +176
  • Oct 05

    12:00 PM

    • 10209
    • Houston Texans
    • +363
    • 10210
    • Indianapolis Colts
    • -127
    • 10211
    • Jacksonville Jaguars
    • +485
    • 10212
    • Tennessee Titans
    • +645
  • Oct 05

    12:00 PM

    • 10213
    • Denver Broncos
    • +1550
    • 10214
    • Kansas City Chiefs
    • -185
    • 10215
    • Los Angeles Chargers
    • +207
    • 10216
    • Oakland Raiders
    • +2000
  • Oct 05

    12:00 PM

    • 10241
    • Dallas Cowboys
    • +148
    • 10242
    • New York Giants
    • +1500
    • 10243
    • Philadelphia Eagles
    • +111
    • 10244
    • Washington Redskins
    • +600
  • Oct 05

    12:00 PM

    • 10245
    • Chicago Bears
    • +167
    • 10246
    • Detroit Lions
    • +1275
    • 10247
    • Green Bay Packers
    • +210
    • 10248
    • Minnesota Vikings
    • +225
  • Oct 05

    12:00 PM

    • 10249
    • Atlanta Falcons
    • +350
    • 10250
    • Carolina Panthers
    • +620
    • 10251
    • New Orleans Saints
    • -184
    • 10252
    • Tampa Bay Buccaneers
    • +1250
  • Oct 05

    12:00 PM

    • 10253
    • Arizona Cardinals
    • +3500
    • 10254
    • Los Angeles Rams
    • -167
    • 10255
    • San Francisco 49ers
    • +470
    • 10256
    • Seattle Seahawks
    • +295

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