2025 Iowa State Cyclones Week 2 Betting Lines
The Iowa State Cyclones opened their 2025 campaign in Ireland against the Kansas State Wildcats. It was a difficult opening assignment against one of the favorites to win the Big 12 Conference. Iowa State scored an impressive win. They were more prepared and made fewer mistakes. The win epitomized the difference-maker that head coach Matt Campbell is. This week brings the intrastate showdown against the hated Iowa Hawkeyes. Iowa State has struggled in this series but seems poised to make a serious threat on Saturday. Iowa’s offense remains a slog. The Hawkeyes will never change under Kirk Ferentz.
Iowa State vs. Iowa Week 2 Betting Lines
Spread: Iowa State -3
Total: 41
Money Line: Iowa State -150, Iowa +130
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Iowa State Weekly Matchup
On Saturday, September 6, 2025, the Iowa State Cyclones will host the Iowa Hawkeyes at Jack Trice Stadium in Ames, IA. Kickoff time is noon ET, with television coverage on FOX.
Last week, the Iowa Hawkeyes won 34-7 against Albany as 39-point home favorites. The game went under the total of 49. Even when Mark Gronowski did something right in his Iowa football debut, something went wrong. It was that kind of Saturday for the South Dakota State transfer and the Hawkeyes.
On a second-and-goal from Albany’s 1-yard line midway through the third quarter, Gronowski took a shotgun snap and powered up the middle for his first rushing touchdown as a Hawkeye. But shortly after he got up to be celebrated by his teammates, he fell back to the ground.
Gronowski exited midway through the third quarter after cramping again and didn't return. He finished with this stat line: 8-for-15 passing for 44 yards and a touchdown; 11 rushes for 39 yards and a touchdown. Against Albany, a team he throttled in the 2023 FCS semifinals, those stats behind a stellar FBS offensive line were disappointing.
Iowa State Weekly Recap
In last week’s home opener, the Iowa State Cyclones won 55-7 against the South Dakota Coyotes as 16.5-point home favorites. The game went over the total of 47.5. Quarterback Rocco Becht delivered one of the most efficient performances in program history, completing 19 of 20 passes for 278 yards and three touchdowns. His 95 percent completion rate set a school record, and he extended his streak to 20 consecutive games with a touchdown pass.
Becht found tight end Benjamin Brahmer for two scores, while Gabe Burkle added a 16-yard touchdown reception. Brahmer finished with seven catches for 47 yards, and Burkle led the team in receiving yards with 85. The Cyclones leaned heavily on their tight ends once again, with 13 of 23 completions going to the position group.
The highlight of the first half came when kicker Kyle Konrardy drilled a 63-yard field goal as time expired, setting both a school and stadium record. The kick ranks as the second-longest in Big 12 history.
South Dakota briefly tied the game at 7-7 when quarterback Aidan Bouman connected with Larenzo Fenner for a six-yard touchdown. Bouman, a former Iowa State reserve, finished 15 of 29 for 126 yards with one score and two interceptions. That would be the Coyotes’ lone highlight, as the Cyclones responded with 48 unanswered points.
Iowa State’s rushing attack took over in the second half. Dylan Lee led all rushers with 81 yards and a touchdown. Abu Sama III, Xavier Townsend, and freshman quarterback Alex Manske each added scores on the ground.
The Cyclones dominated statistically, outgaining South Dakota 529-209 and forcing two turnovers. Special teams also shone, with Aidan Flora producing punt returns of 66 and 51 yards.
2025 Iowa State Cyclones Football Schedule
| DATE |
OPPONENT |
SCORE |
RECORD |
| Aug 23 |
vs. Kansas State Wildcats (Dublin, Ireland) |
W 24-21 |
1-0 |
| Aug 30 |
vs. South Dakota Coyotes |
W 55-7 |
2-0 |
| Sep 6 |
vs. Iowa Hawkeyes |
- |
- |
| Sep 13 |
at Arkansas State Red Wolves |
- |
- |
| Sep 20 |
OFF |
| Sep 27 |
vs. Arizona Wildcats |
- |
- |
| Oct 4 |
at Cincinnati Bearcats |
- |
- |
| Oct 11 |
at Colorado Buffaloes |
- |
- |
| Oct 18 |
OFF |
| Oct 25 |
vs. BYU Cougars |
- |
- |
| Nov 1 |
vs. Arizona State Sun Devils |
- |
- |
| Nov 8 |
at TCU Horned Frogs |
- |
- |
| Nov 15 |
OFF |
| Nov 22 |
vs. Kansas Jayhawks |
- |
- |
| Nov 29 |
at Oklahoma State Cowboys |
- |
- |
The Iowa State Cyclones do not have a storied history when compared to other programs. Since the program's founding in 1895, Iowa State has achieved only three Top 25 finishes. Iowa State has had some notable former coaches who, unfortunately, gained fame at other schools after using Iowa State as a stepping-stone. Johnny Majors and Earl Bruce are two of those famed coaches who found national notoriety at other programs.
Majors and Bruce led Iowa State to its first four bowl games in the 1970s, before a long, dark period of postseason misery ensued. However, since 2000, Iowa State has appeared in 13 bowl games. For Iowa State, a bowl season is about as good as it gets.
Matt Campbell’s arrival in 2016 changed program expectations somewhat. Campbell has produced bowl games in six of the past seven seasons. In 2020, Iowa State achieved its best final ranking to date, 9th. However, Iowa State has proven to be a challenging environment in which to sustain such success. Campbell has done as good a job as is humanly possible. Iowa State fans love that he turned down NFL and bigger-name college jobs to stay in Ames. As long as Campbell is on the sidelines, Iowa State will be a dangerous team.
2025-2026 College Football Schedule
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