2025 Missouri Tigers Week 2 Betting Lines
Once upon a time, the Missouri Tigers and Kansas Jayhawks had one of the most bitter and intense rivalries in college football. It was a rivalry celebrated for its historic context. In fact, Mizzou and KU had the oldest college football rivalry west of the Mississippi River. However, because of conference realignment, Missouri and Kansas last met in 2011. But that ends on Saturday afternoon in Columbia, MO. Faurot Field will host the renewal of hate, rage, and college football passion. Not to mention two aspiring teams for the College Football Playoff. But while KU is firing on all cylinders, Mizzou is missing its potential starting QB.
Missouri vs. Kansas Week 2 Betting Lines
Spread: Missouri -6
Total: 51
Money Line: Missouri -225, Kansas +188
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Missouri Tigers Weekly Matchup
On Saturday, September 6, 2025, the Missouri Tigers will host the Kansas Jayhawks at Faurot Field in Columbia, MO. Kickoff time is 3:30 p.m. ET, with television coverage on ESPN2.
In their last game, the Kansas Jayhawks won 46-7 against Wagner as 46.5-point home favorites. The game went under the total of 57.5.
Kansas easily defeated FCS opponent Wagner on Friday night at remodeled David Booth Kansas Memorial Stadium. The game was not in doubt after Kansas went up 29-0 midway through the second quarter. But the Jayhawks were not immune from mistakes. They’ll need to clean up those mistakes as they renew their rivalry with Missouri next Saturday in Columbia, Mo. The two former conference rivals will square off next Saturday for the first time since 2011, when Missouri left the Big 12 for the SEC.
The Jayhawks had a red-zone interception late in the second quarter and fumbled at the Wagner goal line in the fourth quarter. They were just 4-of-10 on third down. They also gave up a long touchdown on a fourth-down conversion by Wagner.
Wagner quarterback Jack Stevens was 13-of-20 for 90 yards and a touchdown.
Leading 29-7 at halftime, Kansas resumed its dominance on its first possession of the second half, going 75 yards in two plays. Jalon Daniels found Emmanuel Henderson Jr. on a 62-yard bomb for the score.
That ended Daniels’ night with 280 passing yards on 18-of-25 passes. He also threw four touchdowns, including two to Henderson, plus the interception.
Missouri Tigers Weekly Recap
Last game, the Missouri Tigers won 61-6 against Central Arkansas as 38.5-point home favorites. The game went over the total of 52.5.
Beau Pribula accounted for 348 total yards and four touchdowns Thursday night as Missouri waxed Central Arkansas in each team’s season opener in Columbia, Mo.
A Penn State transfer, Pribula completed 23 of 28 passes for 283 yards and two touchdowns while rushing 10 times for 65 yards and two scores. Pribula entered the season in a battle for the starting job with holdover backup Sam Horn.
Tigers coach Eli Drinkwitz planned to play Pribula the first half and Horn the second half, then make a decision on a permanent starter for the Sept. 6 visit from Kansas. However, Horn never got his chance in the second half because he came in to run one play in the first quarter and was promptly knocked out with a leg injury. After halftime, Horn was seen on the sideline with a leg cast and crutches.
Pribula started out with the biggest possible bang, throwing his first pass of the year 49 yards to Marquis Johnson for a touchdown just 3:54 into the game.
Blake Craig bombed field goals of 49 and 55 yards on the Tigers’ next two possessions, and Pribula followed with a 31-yard scoring jaunt with 6:48 left in the half. Pribula then led the team on the first of two 99-yard touchdown drives, capping it with a 1-yard flip to Brett Norfleet with eight seconds remaining for a 26-0 halftime lead.
2025 Missouri Tigers Football Schedule
| DATE |
OPPONENT |
SCORE |
RECORD |
| Aug 28 |
vs. Central Arkansas Bears |
W 61-6 |
1-0 |
| Sep 6 |
vs. Kansas Jayhawks |
- |
- |
| Sep 13 |
vs. Louisiana Ragin Cajuns |
- |
- |
| Sep 20 |
vs. South Carolina Gamecocks |
- |
- |
| Sep 27 |
vs. UMass Minutemen |
- |
- |
| Oct 4 |
OFF |
| Oct 11 |
vs. Alabama Crimson Tide |
- |
- |
| Oct 18 |
at Auburn Tigers |
- |
- |
| Oct 25 |
at Vanderbilt Commodores |
- |
- |
| Nov 1 |
OFF |
| Nov 8 |
vs. Texas A&M Aggies |
- |
- |
| Nov 15 |
vs. Mississippi State Bulldogs |
- |
- |
| Nov 22 |
at Oklahoma Sooners |
- |
- |
| Nov 29 |
at Arkansas Razorbacks |
- |
- |
You can’t talk about Missouri Tigers football without mentioning Don Faurot. Faurot is the namesake of the field on which Mizzou currently plays and was associated with the university for over 80 years. He is the second all-time wins leader for the university, with 101 wins over his coaching career, and led the team to four major bowl games during his 18-year tenure.
Dan Devine helped Mizzou football stay relevant and led the school to its first bowl victory in the 1960 Orange Bowl. He was 92-38-7 during his time in Columbia and led the team to its first Top 5 finish in program history, too.
The man most associated with Mizzou's football success in the modern era is Gary Pinkel. Pinkel left as the winningest coach in school history after the 2015 season and shepherded the program into the SEC.
Many believed that Mizzou would be cannon fodder when making the jump from the Big 12 to the SEC, but it won SEC East titles in 2013 and 2014, solidifying the Tigers' status in the conference. Pinkel produced five double-digit win seasons from 2007 through 2014.
In 2023, Eli Drinkwitz led the first Top Ten finish since Pinkel’s 2013 Mizzou team. Drinkwitz was facing a do-or-die season in his fourth year and delivered one of the best campaigns in Mizzou history. Now he is firmly entrenched as a respected leader.
2025-2026 College Football Schedule
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