College Football Week 13 Best Bets - Football Lines
Week 13 college football arrives with the playoff races tightening and marquee matchups spread across the country. The primetime spotlight falls on the Pac-12, where Oregon hosts USC in Eugene in a clash that could shape the playoff bracket. Dante Moore and the Ducks have surged behind a balanced attack and one of the nation’s best defenses, while Lincoln Riley’s Trojans bring their explosive passing game and postseason hopes into a hostile environment.
In the Big Ten, No. 1 Ohio State welcomes Rutgers to Columbus in a noon kickoff. Julian Sayin continues to lead the Buckeyes’ high-powered offense, while the defense has been dominant all season. Rutgers enters with bowl eligibility secured but will need its best effort to challenge the nation’s top team. The atmosphere at the Horseshoe should be electric as Ohio State looks to stay perfect and lock down its path to the conference championship game.
NBC has a spotlight game with Notre Dame hosting Syracuse. The Irish, riding momentum from a convincing win over Pitt, are pushing toward a playoff berth behind quarterback C.J. Carr and a deep receiving corps. Syracuse, meanwhile, arrives with upset intentions and a chance to spoil Notre Dame’s postseason push. With both teams fighting for position, this matchup carries weight well beyond the standings.
Down in Gainesville, Tennessee visits Florida in a rivalry clash with SEC implications. The Volunteers have leaned on their ground game and opportunistic defense to stay in contention, while the Gators look to rebound from a rocky stretch and protect their home turf. The intensity of this rivalry ensures a physical battle, and the outcome could swing bowl positioning and conference momentum heading into the final week.
Week 13 delivers the type of high-stakes college football that defines championship seasons, with prime television coverage across all major networks ensuring fans won't miss any of the action. From afternoon clashes to primetime spectacles, the weekend promises the kind of memorable moments that college football fans live for, with multiple games carrying both immediate and long-term consequences for the playoff chase.
College Football Betting Lines
Let’s look at the Week 13 college football schedule and spotlight Syracuse at No. 9 Notre Dame on NBC No 16 USC at No. 6 Oregon on CBS, and No. 20 Tennessee at Florida on ABC.
Ready to Bet on College Football?
Bet 2025 College Football odds at BookMaker—spreads, totals, player props, and championship futures all season long.
* Trusted by sharp bettors for over 30 years
* Early odds, fast payouts, and Bitcoin betting
* Live betting and mobile-optimized sportsbook
* Don’t just watch the action — bet on it!
* Sign Up Now and lock in your College Football picks today!
2025-2026 College Football Week 13 Schedule
Tuesday, November 18, 2025
Akron at Bowling Green | ESPNU | 7 p.m.
UMass at Ohio | CBSSN | 7 p.m.
Western Michigan at Northern Illinois | ESPN2 | 7 p.m.
Wednesday, November 19, 2025
Miami (Ohio) at Buffalo | ESPN2 | 7 p.m.
Central Michigan at Kent State | ESPNU | 7 p.m.
Thursday, November 20, 2025
Louisiana at Arkansas State | ESPN | 7:30 p.m.
Friday, November 21, 2025
Florida State at NC State | ESPN | 8 p.m.
Hawai'i at UNLV | FS1 | 10:30 p.m.
Saturday, November 22, 2025
Samford at Texas A&M | SECN+ |12 p.m.
Missouri at Oklahoma | 12 p.m.
Delaware at Wake Forest | ACC Network | 12 p.m.
Tulsa at Army | CBSSN | 12 p.m.
Rutgers at Ohio State | FOX | 12 p.m.
Miami (Fla.) at Virginia Tech | ESPN | 12 p.m.
Louisville at SMU | ESPN2 | 12 p.m.
Minnesota at Northwestern | BTN | 12 p.m.
Kansas at Iowa State | FS1 | 12 p.m.
Charlotte at Georgia | SEC Network | 12:45 p.m.
Old Dominion at Georgia Southern | ESPN+ | 1 p.m.
Washington State at James Madison | ESPN+ | 1 p.m.
Baylor at Arizona | TNT | 1 p.m.
Eastern Illinois at Alabama | SECN+ | 2 p.m.
Mercer at Auburn | SECN+ | 2 p.m.
Missouri State at Kennesaw State | ESPN+ | 2 p.m.
Nevada at Wyoming | 2 p.m.
Ball State at Toledo | ESPN+ | 2 p.m.
Marshall at Appalachian State | ESPN+ | 2:30 p.m.
UConn at Florida Atlantic | ESPN+ | 3 p.m.
Liberty at Louisiana Tech | ESPN+ | 3 p.m.
Sam Houston at Middle Tennessee | ESPN+ | 3 p.m.
New Mexico State at UTEP | ESPN+ | 3 p.m.
South Florida at UAB | ESPN+ | 3 p.m.
Syracuse at Notre Dame | NBC/Peacock | 3:30 p.m.
Notre Dame enters Week 13 with one of the nation’s most efficient offenses, averaging 458.2 yards and 38.5 points per game while committing just 10 turnovers. C.J. Carr leads the passing attack with 2,487 yards, and Jeremiyah Love has powered the ground game with 1,135 rushing yards and 14 touchdowns. The Irish defense has been equally strong, ranking 13th nationally against the run and allowing only 18.4 points per game, with 17 takeaways to keep opponents off balance. Notre Dame is 5-4-1 ATS and 5-5 O/U.
Syracuse has struggled throughout ACC play, averaging just 22.3 points per game and ranking near the bottom nationally in turnovers (20, 130th). The Orange defense has been porous, giving up 430.6 yards and 31.5 points per game, including 267.1 passing yards allowed per contest. With Notre Dame balanced on both sides of the ball, Syracuse will need to protect the football and find explosive plays to stay competitive. Syracuse is 4-5-1 ATS and 5-5 O/U.
3:30 p.m. | Kentucky at Vanderbilt
3:30 p.m. | Jacksonville State at Florida International | CBSSN
3:30 p.m. | Southern Miss at South Alabama | ESPN+
USC at Oregon | CBS | 3:30 p.m.
This showdown in Eugene carries massive playoff implications. USC brings one of the nation’s most explosive offenses into Eugene, averaging 488.9 yards and 38.2 points per game. The Trojans have been balanced with 298.1 passing yards and 190.8 rushing yards per game, but their defense has been inconsistent, allowing 344.1 yards and 21.7 points per contest. Turnovers have been manageable at 12, though the unit has forced only 10 takeaways. USC is 5-5 ATS and 5-5 O/U.
Oregon counters with a top-10 scoring offense of its own, averaging 475.4 yards and 39.0 points per game while committing just eight turnovers. The Ducks’ defense has been elite, ranking No. 1 nationally in pass defense (127.3 yards allowed per game) and sixth in scoring defense (13.7 points allowed). With both teams sitting at 6-1 in Big Ten play, this matchup is a direct test of USC’s passing attack against Oregon’s secondary. Oregon is 5-4-1 ATS and 5-5 O/U.
3:30 p.m.| Arkansas at Texas | ABC
3:30 p.m. | Michigan State at Iowa | FS1
3:30 p.m. | Duke at North Carolina | ACC Network
3:30 p.m. | East Carolina at UTSA | ESPN+
3:45 p.m. | Tulane at Temple | ESPNU
4 p.m. | Oklahoma State at UCF | ESPN+
4 p.m. | Georgia State at Troy | ESPN+
4 p.m. | Kansas State at Utah | ESPN2
4 p.m. | Michigan at Maryland | BTN
4 p.m. | TCU at Houston | FOX
4:15 p.m. | Coastal Carolina at South Carolina | SEC Network
4:30 p.m. | Furman at Clemson | The CW Network
5 p.m. | UL Monroe at Texas State | ESPN+
7 p.m. | New Mexico at Air Force | CBSSN
7 p.m. | Pitt at Georgia Tech | ESPN
7 p.m. | Nebraska at Penn State | NBC
7 p.m. | Colorado State at Boise State | FS1
7:30 p.m. | Cal at Stanford | ACC Network
Tennessee at Florida | ABC | 7:30
Tennessee enters with one of the nation’s most prolific offenses, ranking second in scoring at 43.4 points per game and third in total offense at 495.0 yards. The Volunteers average 318.3 passing yards and 176.7 rushing yards per game, though turnovers (15, rank 101) have been an issue. Defensively, Tennessee has been vulnerable against the pass, allowing 260.2 yards per game and nearly 29 points per contest. Tennessee is 3-6-1 ATS and 7-3 O/U.
Florida has struggled offensively, averaging just 20.8 points and 339.5 total yards per game, with 17 turnovers (rank 120). The Gators’ defense has been steadier, allowing 366.3 yards and 23.6 points per game, but they have forced only nine takeaways. With Tennessee’s high-powered attack facing Florida’s middling defense, the Volunteers hold the statistical edge, though their pass defense could give the Gators opportunities. Florida is 3-6-1 ATS and 4-6 O/U.
7:30 p.m. | Illinois at Wisconsin | BTN
7:30 p.m. | North Texas at Rice | ESPNU
7:45 p.m. | Western Kentucky at LSU | SEC Network
8 p.m. | BYU at Cincinnati | FOX
8 p.m. | Arizona State at Colorado | ESPN2
10:30 p.m. | Utah State at Fresno State | CBSSN
10:30 p.m. | Washington at UCLA | NBC
10:30 p.m. | San Jose State at San Diego State | FS1
2025-2026 College Football Schedule
Did You Know?
At BookMaker, we go beyond just providing top-notch sports betting options! Take advantage of these exclusive features and rewards:
BookMaker ATM Card for seamless transactions: Easily access your funds with the BookMaker ATM card, providing instant access to your winnings and secure transactions wherever you go.
Loyalty Levels & BetPoints Programs for additional rewards: Earn BetPoints as you bet, and unlock exciting perks at higher loyalty levels. The more you play, the more you earn!
Seasonal and Reload Bonuses to maximize your earnings: Stay ahead with seasonal promotions and reload bonuses, boosting your bankroll throughout the year.
Early Cashout Option for added flexibility: Cash out your bet early and lock in profits or limit losses—putting you in control of your wagers.
Free Crypto Payouts for fast and secure withdrawals: Enjoy fast, secure withdrawals with zero fees when you choose crypto payouts.
Open Play Option for unique parlay betting: Get creative with your parlays using the Open Play option, offering more ways to win.
Casino Promotions & Contests for extra fun and wins: Join in on exclusive casino promotions and contests, adding excitement to your betting experience.
8% Cash Back on all your horse racing bets: Place horse racing bets and get 8% cash back on your losses, making it easier to bounce back.
Explore all these benefits and more at BookMaker!
Betting Rules & Policies
Free Play Rules
- Free plays cannot be used on proposition bets.
- Free Plays do not earn any BetPoints™
- Bets made using Free Plays do not count towards completing any rollovers. (Free Plays are always subject to a rollover of their own. You must complete the required rollover prior to making a withdrawal).
- The maximum payout for any Free Play is $5,000.
- Free Plays that are left unused for 180 days will be removed from your account.
ROLLOVER
- Did you know that on all deposits made at BookMaker, there is a rollover requirement: an amount of betting action you must fulfill before you are eligible to make a withdrawal.
- Did you know that rollovers are calculated by multiplying the amount initially credited to your account a certain number of times? Yes! If you deposit without claiming any bonus, the rollover will always be 1x (one-time) your deposit amount. If you do claim a deposit bonus, the rollover will be higher and is based on the deposit plus bonus amount.
Wager disputes (claims)
If you disagree with any aspect of a wager you’ve placed, you are welcome to log an official dispute (commonly known as a “claim”). Claims must be reported no later than 15 (fifteen) calendar days following the settlement of the wager.
If following an initial review of the case there remains any doubt regarding the wager type, line, market, amount, or any other detail, the claim will be escalated to the BookMaker management team. All decisions made by them are final.
Wager Cash Out - How it works
With the Cash Out feature you can choose to eliminate a wager that's already been placed, and receive back either a portion, or your full stake amount.
Cash Out is selectively available on certain events, fixtures, and markets.
In order to see if a wager is eligible to be cashed out, simply navigate to your Bet Slip and check the 'My Open Bets' tab. If eligible, the Cash Out button will be displayed.
It’s also important to note that Cash Out is not contributing to any bonus or promotion including Bet Point accumulation and Rollover for releasing bonus cash.
