Louisville Cardinals College Football Betting
Nearly all the success enjoyed by the Louisville football program has taken place in the last two decades. Since 1998, the Cardinals have appeared in 16 of the program’s 21 bowl games, and they’ve had just two losing seasons in that span. The Cards have also been a member of four conferences in that stretch, but appear to have found a home in the ACC.
The Cardinals made their first bowl game a success by beating Drake in the Sun Bowl following the 1957 season. It would be 13 more seasons before the Cards returned to a bowl and 33 more before they notched another win. The Cards had their first 10-win season and won the Fiesta Bowl in 1999.
Coach John L. Smith began to transform the program into a national powerhouse in the late 1990s, stringing together five consecutive winning seasons and bowl games, leaving the club in good shape for Bobby Petrino’s first stint. The Cards won 41 games in four years and earned their highest ranking ever in the AP poll, reaching a peak of No. 3. Following a program record 12 wins and an Orange Bowl victory in 2006, Petrino left for the NFL. Petrino returned in 2014, and the Cards won at least eight games in each of his four seasons. Lamar Jackson won a Heisman Trophy under Petrino in 2016.
After a 2018 collapse, Petrino was fired, and Scott Satterfield struggled to break out. After Satterfield fled to Cincinnati one step ahead of the posse, Louisville found the perfect fit in native son Jeff Brohm.
College Football Betting Lines
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2025 Louisville Cardinals Football Schedule
| DATE |
OPPONENT |
| Aug 30 |
vs. Eastern Kentucky Colonels |
| Sep 5 |
vs. James Madison Dukes |
| Sep 13 |
OFF |
| Sep 20 |
vs. Bowling Green Falcons |
| Sep 27 |
at Pitt Panthers |
| Oct 4 |
vs. Virginia Cavaliers |
| Oct 11 |
OFF |
| Oct 17 |
at Miami-FL Hurricanes |
| Oct 25 |
vs. Boston College Eagles |
| Nov 1 |
at Virginia Tech Hokies |
| Nov 8 |
vs. California Golden Bears |
| Nov 14 |
vs. Clemson Tigers |
| Nov 22 |
at SMU Mustangs |
| Nov 29 |
vs. Kentucky Wildcats |
2025-2026 College Football Schedule
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