2025 Monday Night Football Best Bets - NFL Lines & Picks

2025 NFL Monday Night Football Week 13 Betting Lines

A busy Holiday weekend of NFL action concludes on Monday Night Football with a Week 13 clash between the New York Giants and New England Patriots. It’s been more than 15 years but the G-Men are remembered for one notable win in the series. Playing as a big underdog the Giants upset the Pats, 17-14, in Super Bowl XLII, ending what was realistically the last chance a team had of completing a perfect season. Led by Tom Brady New England went 16-0 during the regular season that included a 38-35 win over the Giants in the regular season finale.

The Giants won’t be competing for a Super Bowl this season since they became the first team officially eliminated from playoff contention. New York suffered its sixth straight defeat blowing a 10-point fourth quarter lead against Detroit on Sunday. Late game collapses are nothing new to the Giants, who also allowed 33 fourth quarter points in a loss to Denver in Week 7 and they’ve lost five games after holding a lead in the final frame. The game at Gillette Stadium in Foxboro, MA kicks off at 8:15 p.m. ET on December 1 and will air on ESPN.

Giants at Patriots MNF Week 13 Lines

Spread: Patriots -7

Total: 47

Money Line: Giants +286 / Patriots -357

Giants at Patriots Betting Preview

A change at head coach didn’t solve the losing issue for the Giants so the club went another direction. After yet another late game meltdown, the Giants relieved defensive coordinator Shane Bowen of his duties. The Giants allow 27.8 points and 385 yards a game to rank 30th in the NFL in both categories. Four times during their current 6-game losing streak an opponent scored more than 30 points.

It wasn’t just the yards and points allowed that led to a staff shakeup. Following a loss to the Bears in Week 10, Brian Daboll was fired as head coach with Mike Kafka named the interim. Half of New York’s 10 losses have come after the Giants led by at least 10 points with all of them on the road. The setback in Detroit was New York’s 12th straight on the road dating back to last season.

With Jaxon Dart injured the Giants turned to former No. 1 overall draft pick Jameis Winston as their QB1. Winston threw for 366 yards and with a touchdown and had a 33-yard TD reception as the Giants dug deep into their bag to trick plays. At 2-10 and with nothing to lose it makes sense that they try whatever they can. However, questionable play calling in the Detroit game backfired and there are some things you just can’t do.

The Patriots enter Week 13 with nine straight wins and the best record in the NFL at 10-2. Both defeats came at home to Las Vegas in the season opener and Pittsburgh in Week 3. You can also question the level of opposition during the current winning streak. Only two of the nine teams have a winning record entering Week 13 while the other five are a combined 21-57. The best win over that span is against the 7-4 Bills.

You still have to win the games and the Pats have done that with an efficient offense and strong defense. Drake Maye leads the NFL with 3,130 passing yards while completing 71 percent of his passes. He’s tossed 21 TDs and has been picked off only six times. An alarming stat is that Maye has been sacked 37 times, the third-most in the NFL.

The defense doesn’t give up a lot. The Pats have allowed more than 23 points in a game once, beating Miami 33-27 in Week 2, and they boast the sixth-best scoring defense allowing 18.8 points per game. Marcus Jones had a pick-six in the Pats’ 26-20 win over Cincinnati on Sunday, though New England failed to cover the spread for the second straight game for the third time in their last four outings.

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