2018 College Football Week 2 Betting - NCAA Football Spreads

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2018 College Football Week 2 Betting Odds

An early clash in the Pac-12 and the first real test for Jimbo Fisher and his Texas AM Aggies highlight Week 2 of the college football schedule. It’s rare to see a conference game this early in the season, but the USC Trojans and Stanford Cardinal will get a taste of league action when the two meet on the Farm. It’s been a contentious rivalry since the days of Jim Harbaugh and Pete Carroll and things have carried over, on the field at least. USC won its first conference title last season, but the Trojans will look much different with Sam Darnold and Ron Jones off to the NFL. How their replacements fare will determine if the Trojans can win another crown.

Eight wins just doesn’t cut it in College Station and after three straight seasons with that many victories, Kevin Sumlin was given the boot. Fisher gets his first test when the Aggies host Clemson in the marquee matchup of the week. Two years removed from a National Championship, the Tigers are one of college football’s top teams under Dabo Swinney, going 40-4 in the last three seasons. There’s nothing like a rivalry game to spice things up and we get a meeting between former Big 8/12 teams when Colorado heads to Nebraska. This was one of the best games when the two were in the conference, but they’ve gone their separate ways. The Huskers are looking to get back to being relevant under new coach Scott Frost. Penn State and Pitt will battle for bragging rights in the state of Pennsylvania.

2018 NCAA Football Week 2 Betting Schedule

September 4th, 2018 to September 10th, 2018

Friday, September 7

TCU at SMU, 8 p.m. ET

Week Two opens on Friday night with a perennial Big 12 Conference title contender against a Group of Five team coming off its first bowl in five years but with a history that shows the inability to sustain success. The TCU Horned Frogs are always in the hunt to win the Big 12 and are expected to be a Top 25 team yet again. Known for strong defenses the Frogs must break in a new quarterback for 2018. The SMU Mustangs are known for their ability to score but also for an inability to even field a mediocre defense. And with new head coach Sonny Dykes that impression is hardly going to change. More

Saturday, September 8

UTEP at UNLV, TBD

Rice at Hawai'i, TBD

New Mexico State at Utah State, TBD

Liberty at Army, 12 p.m. ET

Eastern Michigan at Purdue, 12 p.m. ET

New Mexico at Wisconsin, 12 p.m. ET

Week Two pits a questionable and overmatched New Mexico Lobos team against the mauling power of the Big Ten West. The Wisconsin Badgers are picked by many to make the College Football Playoff and last week only served to reinforce those lofty expectations. With the best and most experienced offensive line in the country Wisconsin should curb stomp the Lobos. The only question is whether or not this is an overlay. As last week demonstrated the Badgers can dominate while still not quite being able to get the money. More

Mississippi State at Kansas State, 12 p.m. ET

We’ve seen schools bow to corporations to sell their stadium naming rights, or slap the name of a gracious donor on the site. Sometimes the sacred ground gets the name of a legendary coach, but rarely is that coach still roaming the sidelines. Bill Snyder retired following the 2005 season as the Kansas State Wildcats winningest coach. Four years later he was back running the show, doing it inside Bill Snyder Family Stadium. Snyder and his Cats get a big test from the Mississippi State Bulldogs in Week 2 of the college football season. More

Nevada at Vanderbilt, 12 p.m. ET

Arizona at Houston, 12 p.m. ET

The Kevin Sumlin era in the desert got off to a rocky start with the Arizona Wildcats losing their opener last week to BYU. Looking to put the Rich Rodriguez scandal-laden tenure behind them, UA made a great hire getting the former Texas AM coach to come to Tucson. Sumlin actually began his head coaching career with the Houston Cougars in 2008, restoring that program back to national prominence. Sumlin returns to his old stomping grounds in Week 2 for the first time since leaving for College Station. More

Western Michigan at Michigan, 12 p.m. ET

Week two includes a once great program that is still struggling to get back to its former elite status. Once again, the Michigan Wolverines hype machine served copious amounts of Kool aid this past offseason promising a new look and better results. Yet once again coach Jim Harbaugh’s Wolverines failed to deliver the goods on the nation’s biggest stage last week in a loss at Notre Dame. Now discredited yet again the Maize and Blue will play their home opener against the Western Michigan Broncos. Harbaugh and Michigan have much to answer for and may find WMU’s leaky defense the perfect remedy for their woes. More

Duke at Northwestern, 12 p.m. ET

Two of the brainiest schools in the nation will square off in Week 2 of the 2018 college football season when the Northwestern Wildcats host the Duke Blue Devils. Both teams are coming off impressive wins in their season openers. Northwestern was a one-point road favorite per the CFB betting odds on the road against Purdue last Thursday and held on for a 31-27 win, while Duke scored a comfortable win and covered the NCAAF betting line in a 34-14 victory over Army. One team will move to 2-0 after this one. More

Georgia Tech at South Florida, 12 p.m. ET

The Georgia Tech Yellow Jackets and South Florida Bulls each cruised to wins in their season openers on Saturday. South Florida had little trouble getting past a feisty Elon Phoenix team by a margin of 34-14, while Georgia Tech ran over Alcorn State 41-0 with some eye-popping numbers on the ground. Each of these teams is looking to get to 2-0 with a win in their Week 2 match-up. This will be the first-ever meeting between these two programs. More

Georgia State at North Carolina State, 12:30 p.m. ET

UCLA at Oklahoma, 1 p.m. ET

The Oklahoma Sooners looked incredibly sharp in their season-opening win against Florida Atlantic. Many analysts, including yours truly, expected the Owls to give the Sooners all they could handle. However, the Sooners were more than up to the challenge, jumping out to a 42-0 halftime lead in an eventual 63-14 rout where OU easily covered the CFB betting line. More

Air Force at Florida Atlantic, 2 p.m. ET

The Lane Train ran off the tracks shortly after it crossed the Mississippi River in the season opener for the Florida Atlantic Owls. Many bettors tore up their FAU tickets by halftime in a 63-14 defeat at the hands of Oklahoma. The Owls didn’t even come close to covering the CFB betting line in the loss, but they are decent favorites against the Air Force Falcons this week. More

Kansas at Central Michigan, 3 p.m. ET

Rutgers at Ohio State, 3:30 p.m. ET

The Ohio State Buckeyes showed that they didn’t need Urban Meyer on the sidelines in a 77-31 rout of Oregon State in their season opener. Ohio State moved the ball with ease all day long as Dwayne Haskins looked solid throughout the first game of the season. The Rutgers Scarlet Knights are off to a good start too with a win in their FBS opener for the first time since 2014. However, it’s going to be tough for Rutgers to keep it within the number in this Week 2 matchup. More

Colorado at Nebraska, 3:30 p.m. ET

Big Red is still waiting to see Scott Frost’s new offense in action. A severe thunderstorm with 70 MPH winds and copious amounts of lightning caused the Nebraska Cornhuskers’ first game of the season against the Akron Zips to be cancelled last Saturday. Time will tell whether or not that was an ominous indicator of things to come. More

Georgia at South Carolina, 3:30 p.m. ET

Arkansas State at Alabama, 3:30 p.m. ET

Buffalo at Temple, 3:30 p.m. ET

Memphis at Navy, 3:30 p.m. ET

The Navy Midshipmen made the long journey back home from Hawai’i earlier this week, and they are still in search of their first win. Navy was down 28-0 to the Rainbow Warriors after the first 19 minutes of play last Saturday, but the Midshipmen were able to make the final score respectable in a 59-41 loss. That wasn’t good news for anyone who bet on Navy though, as the Midshipmen were a two-touchdown favorite on the NCAAF betting line coming into this one. More

North Carolina at East Carolina, 3:30 p.m. ET

It was a brutal start to the season for the East Carolina Pirates. East Carolina is looking to right the ship after back-to-back 3-9 seasons under Scottie Montgomery, but the Pirates loss to North Carolina A&T is the school’s second straight loss to an FCS opponent to start the year. However, now all the expectations are off coming into this Week 2 meeting with the North Carolina Tar Heels, and that means ECU has nothing to lose. More

Ball State at Notre Dame, 3:30 p.m. ET

Coming into the season, the Notre Dame Fighting Irish were a trendy pick to win the national championship. As SB Nation’s Bill Connelly pointed out, if they got past Michigan in their season opener, they would likely be favored per the CFB betting odds in every game for the remainder of the season. After defeating Michigan 24-17 in the opener, the Irish are now likely to be double-digit favorites on the CFB betting line in every game until a September 29 home tilt against Stanford. More

Southern Illinois at Ole Miss, 4 p.m. ET

Iowa State at Iowa, 5 p.m. ET

One of the most underrated rivalries will add another chapter to its storied legacy when the Iowa Hawkeyes and Iowa State Cyclones meet for the CyHawk Trophy on Saturday afternoon in Week 2 action. This will be the first game of the season for Iowa State. Their opener against South Dakota State was cancelled due to bad weather, so Iowa has no film to break down Matt Campbell’s offense. The Hawkeyes looked sharp in their opener against a very good Northern Illinois team though, easily covering the CFB betting line in a 33-7 win. More

Maryland at Bowling Green, 6 p.m. ET

Youngstown State at West Virginia, 6 p.m. ET

UMass at Georgia Southern, 6 p.m. ET

Appalachian State at Charlotte, 6 p.m. ET

Eastern Kentucky at Marshall, 6:30 p.m. ET

UL Monroe at Southern Mississippi, 7 p.m. ET

UAB at Coastal Carolina, 7 p.m. ET

Baylor at UT San Antonio, 7 p.m. ET

Indiana State at Louisville, 7 p.m. ET

Clemson at Texas A&M, 7 p.m. ET

College Gameday will be deep in the heart of Texas for this week’s Gameday Game. The Texas A&M Aggies and Clemson Tigers are both looking to move to 2-0 in Week 2 after easily dispatching of FCS minnows in their openers. The Aggies had no trouble getting past Northwestern State last Thursday night in a 59-7 rout, while the Tigers thrashed Furman 48-7. This will be the first chance for Jimbo Fisher to prove that he was worth $75 million this offseason. More

Wyoming at Missouri, 7 p.m. ET

Virginia at Indiana, 7:30 p.m. ET

The Virginia Cavaliers and Indiana Hoosiers are each looking to go to 2-0 and take an important step towards bowl eligibility with a win in their Week 2 showdown. Virginia surprised many by getting to a bowl last year after a 2-10 campaign in 2016, and the Wahoos cruised to an easy 42-13 win against FCS Richmond in their opener. Virginia doubled up their opponents in terms of total yardage, and the Cavaliers covered the CFB betting line with ease. More

Arkansas at Colorado State, 7:30 p.m. ET

The Colorado State Rams are staring down the barrel of an 0-3 start. Colorado State was surprisingly upset as a big favorite per the CFB betting odds against Hawai’i in their opener, and the Rams were drubbed by arch-rival Colorado in the Rocky Mountain Showdown last week. Now, they must take on an Arkansas Razorbacks team that is going to score plenty of points in this Week 2 showdown. Arkansas had little trouble cruising past Eastern Illinois in its opener, racing out to a 38-6 halftime lead in an eventual 55-20 win. More

Kentucky at Florida, 7:30 p.m. ET

No team in the country has a longer current winning streak over an opponent than the Florida Gators have over the Kentucky Wildcats. Florida has won 31 straight games over Kentucky coming into Saturday’s Week 2 affair, but the Wildcats have come painstakingly close to finally breaking the curse in three of their last four meetings. A win for Kentucky would send Wildcats’ fans into the stratosphere, while a Florida loss would be a very ominous start to the Dan Mullen era. More

Utah at Northern Illinois, 7:30 p.m. ET

The Northern Illinois Huskies are not afraid to play anyone. Northern Illinois will play three power conference opponents and BYU in its non-conference slate this season, and a win or two would be huge for the program. The Huskies didn’t have much luck in their season opener against the Iowa Hawkeyes, failing to cover in a 33-7 loss even though they were a popular college football betting pick to pull off the upset. They are hoping their fortunes will change at home in a Week 2 clash with the Utah Utes. More

Florida International at Old Dominion, 7:30 p.m. ET

Fresno State at Minnesota, 7:30 p.m. ET

The Fresno State Bulldogs are no strangers to picking off Power Five opponents. During the Pat Hill years, Fresno State’s bread and butter was getting paid to come into your stadium to beat you, and Jeff Tedford has brought that mentality back. The program has come a long way under Tedford in a short amount of time, and that’s why the Minnesota Golden Gophers are on upset alert in Week 2 of the college football season. More

South Alabama at Oklahoma State, 8 p.m. ET

Penn State at Pittsburgh, 8 p.m. ET

We better enjoy it while we can because this nasty rivalry is set to go on hiatus after the 2019 game. The politics and business side of college football are ruining traditional rivalries and this one is next. Two years ago the Penn State Nittany Lions were probably wishing they hadn’t scheduled the Pitt Panthers, with a loss to their Western Pennsylvania rival eventually costing them a spot in the CFP. The Lions made up for that defeat by pounding Pitt last season, evening the series since it resumed following a 16-year layoff. More

Tulsa at Texas, 8 p.m. ET

Cincinnati at Miami (OH), 8 p.m. ET

USC at Stanford, 8:30 p.m. ET

The USC Trojans won their first Pac-12 championship last season and their first conference title since claiming the Pac-10 in 2008 by knocking off the Stanford Cardinal in the league’s title game. That win ended the South Division’s run of futility in the title matchup, giving that side of the conference its first win in seven tries. It also gave the Trojans a sweep of the two games after they cut down the Cardinal in the regular season meeting, ending a three-game losing streak to their Northern California neighbor. The teams get the league slate underway in Week 2. More

California at BYU, 10:15 p.m. ET

UConn at Boise State, 10:15 p.m. ET

Michigan State at Arizona State, 10:45 p.m. ET

Herm Edwards silenced the doubters for at least one week as he made a triumphant return to the sidelines in the Arizona State Sun Devils 49-7 rout of Texas-San Antonio last week. Edwards hadn’t coached a game since 2008 when he was with the NFL’s Chiefs, and he had never been a head coach at the collegiate level until his surprising hire at ASU. The competition gets a bit tougher in Week 2 when the Sun Devils host the No. 15 ranked Michigan State Spartans in a Pac-12/Big Ten showdown in the desert. More

San Jose State at Washington State, 11 p.m. ET

Week 2 College Football Games of the Week

Clemson at Texas AM, Saturday, September 8, 7 p.m. ET (ESPN)

Three consecutive 8-win seasons were enough for the Aggies to make a coaching change. They spent a lot of money to lure Fisher to Texas and to win games just like this one. Fisher will definitely earn his paycheck and if the Aggies pull out a victory, he’ll likely win over the boosters, at least until next week. Jimbo knows what it’s like being in the pressure cooker after taking over for legendary Bobby Bowden at Florida State. He won 106 games in eight seasons with a BCS Championship following the 2014 campaign when the Noles went 14-0.

Swinney and the Tigers have built a dynasty, proving they aren’t just a brief phenomenon. They won before Deshaun Watson and they’ve won after him. Over the last seven seasons the Tigers are 82-11 reaching the CFP in each of the last three years with a National Championship in 2016. Questions remain after a bunch of starters left the program and they could be had while trying to figure things out early in the year. But the Tigers are a talented group and the Aggies will have their hands full.

UCLA at Oklahoma, Saturday, September 8, 1 p.m. ET (FOX)

The Jim Mora era started nicely enough in Westwood, but after two straight losing seasons, the school went with a change of direction for its program. Chip Kelly worked wonders with the Oregon program during his time there, winning 46 games, three Pac-12 championships and playing in the 2011 BCS National Championship Game. He’s entrusted with bringing some success to the Bruins, who haven’t won a conference championship in 20 years. This will be a test for Kelly and his innovative offense, but the Sooners are used to his style of play in the Big 12.

The transition from Bob Stoops to Lincoln Riley went smoothly. Now the Sooners need to transition to a new quarterback after Baker Mayfield was taken with the first overall pick in the NFL draft. Mayfield was good, but he also had a boatload of talent to work with. Riley is an offensive guru himself and will match wits with Kelly in a game that could see plenty of points. The Sooners have Kyler Murray behind center and will put up points. The defense, that’s another story.

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2018 NCAA Football Weekly Schedule

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Live Lines

  • Time
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  • Odds
  • Ago 01

    6:00 AM

    • 10631
    • Devin White
    • +702
    • 10632
    • Nick Bosa
    • +727
    • 10633
    • Quinnen Williams
    • +782
    • 10634
    • Devin Bush
    • +752
    • 10635
    • Ed Oliver
    • +1508
    • 10636
    • Josh Allen
    • +1508
    • 10637
    • Clelin Ferrell
    • +2014
    • 10638
    • Brian Burns
    • +2014
    • 10639
    • Montez Sweat
    • +1508
    • 10640
    • Rashan Gary
    • +2216
    • 10641
    • Jahlani Taval
    • +2014
    • 10642
    • Andraez Williams
    • +2521
    • 10643
    • Jerry Tillery
    • +3030
    • 10644
    • Darnell Savage
    • +2350
    • 10645
    • Jonathan Abram
    • +3540
    • 10646
    • Christian Wilkins
    • +3540
    • 10647
    • Taylor Rapp
    • +3540
    • 10648
    • Deandre Baker
    • +3540
    • 10649
    • Deionte Thompson
    • +4000
    • 10650
    • Nasir Adderley
    • +4500
    • 10651
    • Marquise Blair
    • +4000
    • 10652
    • Juan Thornhill
    • +4000
    • 10653
    • Jachal Polite
    • +4500
    • 10654
    • Byron Murphy
    • +4500
    • 10655
    • Rock Ya-Sin
    • +3540
    • 10656
    • Dexter Lawrence
    • +5000
    • 10657
    • L.J Collier
    • +5000
    • 10658
    • Joejuan Williams
    • +5000
    • 10659
    • Justin Layne
    • +5000
  • Ago 01

    6:00 AM

    • 10601
    • Kyler Murray
    • +196
    • 10602
    • Josh Jacobs
    • +855
    • 10603
    • Mecole Hardman
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    • N Keal Harry
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    • 10605
    • Drew Lock
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    • Daniel Jones
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    • David Montgomery
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    • AJ Brown
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    • Terry McLaurin
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    • Darrell Henderson
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    • 10612
    • Will Grier
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    • Andy Isabella
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    • Dwayne Haskins
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    • 10615
    • Marquise Brown
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    • TJ Hockenson
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    • 10617
    • Miles Sanders
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    • 10618
    • Noah Fant
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    • Deebo Samuel
    • +2154
    • 10620
    • Parris Campbell
    • +2742
    • 10621
    • DK Metcalf
    • +3105
    • 10622
    • JJ Arcega-Whiteside
    • +3727
    • 10624
    • Hakeem Butler
    • +3983
    • 10625
    • Damien Harris
    • +5000
    • 10626
    • Irv Smith
    • +5000
  • Oct 05

    12:00 PM

    • 10001
    • Arizona Cardinals
    • +15000
    • 10002
    • Atlanta Falcons
    • +3593
    • 10003
    • Baltimore Ravens
    • +5700
    • 10004
    • Buffalo Bills
    • +9000
    • 10005
    • Carolina Panthers
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    • 10006
    • Chicago Bears
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    • 10007
    • Cincinnati Bengals
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    • 10008
    • Cleveland Browns
    • +1400
    • 10009
    • Dallas Cowboys
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    • 10010
    • Denver Broncos
    • +9000
    • 10011
    • Detroit Lions
    • +11000
    • 10012
    • Green Bay Packers
    • +1800
    • 10013
    • Houston Texans
    • +4800
    • 10014
    • Indianapolis Colts
    • +985
    • 10015
    • Jacksonville Jaguars
    • +4500
    • 10016
    • Kansas City Chiefs
    • +740
    • 10017
    • Los Angeles Chargers
    • +1400
    • 10018
    • Los Angeles Rams
    • +1250
    • 10019
    • Miami Dolphins
    • +32500
    • 10020
    • Minnesota Vikings
    • +2800
    • 10021
    • New England Patriots
    • +690
    • 10022
    • New Orleans Saints
    • +925
    • 10023
    • New York Giants
    • +10500
    • 10024
    • New York Jets
    • +9000
    • 10025
    • Oakland Raiders
    • +8500
    • 10026
    • Philadelphia Eagles
    • +1525
    • 10027
    • Pittsburgh Steelers
    • +2300
    • 10028
    • San Francisco 49ers
    • +3750
    • 10029
    • Seattle Seahawks
    • +2650
    • 10030
    • Tampa Bay Buccaneers
    • +7953
    • 10031
    • Tennessee Titans
    • +7000
    • 10032
    • Washington Redskins
    • +11500
  • Oct 05

    12:00 PM

    • 10101
    • Baltimore Ravens
    • +2550
    • 10102
    • Buffalo Bills
    • +4500
    • 10103
    • Cincinnati Bengals
    • +8000
    • 10104
    • Cleveland Browns
    • +695
    • 10105
    • Denver Broncos
    • +4300
    • 10106
    • Houston Texans
    • +2550
    • 10107
    • Indianapolis Colts
    • +490
    • 10108
    • Jacksonville Jaguars
    • +2200
    • 10109
    • Kansas City Chiefs
    • +370
    • 10110
    • Los Angeles Chargers
    • +690
    • 10111
    • Miami Dolphins
    • +16000
    • 10112
    • New England Patriots
    • +345
    • 10113
    • New York Jets
    • +4500
    • 10114
    • Oakland Raiders
    • +3950
    • 10115
    • Pittsburgh Steelers
    • +1135
    • 10116
    • Tennessee Titans
    • +3400
  • Oct 05

    12:00 PM

    • 10121
    • Arizona Cardinals
    • +7200
    • 10122
    • Atlanta Falcons
    • +1469
    • 10123
    • Carolina Panthers
    • +2526
    • 10124
    • Chicago Bears
    • +765
    • 10125
    • Dallas Cowboys
    • +1200
    • 10126
    • Detroit Lions
    • +4800
    • 10127
    • Green Bay Packers
    • +845
    • 10128
    • Los Angeles Rams
    • +575
    • 10129
    • Minnesota Vikings
    • +1325
    • 10130
    • New Orleans Saints
    • +350
    • 10131
    • New York Giants
    • +5500
    • 10132
    • Philadelphia Eagles
    • +685
    • 10133
    • San Francisco 49ers
    • +1675
    • 10134
    • Seattle Seahawks
    • +1150
    • 10135
    • Tampa Bay Buccaneers
    • +4350
    • 10136
    • Washington Redskins
    • +5300
  • Oct 05

    12:00 PM

    • 10201
    • Buffalo Bills
    • +1050
    • 10202
    • Miami Dolphins
    • +5500
    • 10203
    • New England Patriots
    • -475
    • 10204
    • New York Jets
    • +555
  • Oct 05

    12:00 PM

    • 10205
    • Baltimore Ravens
    • +325
    • 10206
    • Cincinnati Bengals
    • +1850
    • 10207
    • Cleveland Browns
    • +133
    • 10208
    • Pittsburgh Steelers
    • +176
  • Oct 05

    12:00 PM

    • 10209
    • Houston Texans
    • +363
    • 10210
    • Indianapolis Colts
    • -127
    • 10211
    • Jacksonville Jaguars
    • +485
    • 10212
    • Tennessee Titans
    • +645
  • Oct 05

    12:00 PM

    • 10213
    • Denver Broncos
    • +1550
    • 10214
    • Kansas City Chiefs
    • -185
    • 10215
    • Los Angeles Chargers
    • +207
    • 10216
    • Oakland Raiders
    • +2000
  • Oct 05

    12:00 PM

    • 10241
    • Dallas Cowboys
    • +148
    • 10242
    • New York Giants
    • +1500
    • 10243
    • Philadelphia Eagles
    • +111
    • 10244
    • Washington Redskins
    • +600
  • Oct 05

    12:00 PM

    • 10245
    • Chicago Bears
    • +167
    • 10246
    • Detroit Lions
    • +1275
    • 10247
    • Green Bay Packers
    • +210
    • 10248
    • Minnesota Vikings
    • +225
  • Oct 05

    12:00 PM

    • 10249
    • Atlanta Falcons
    • +350
    • 10250
    • Carolina Panthers
    • +620
    • 10251
    • New Orleans Saints
    • -184
    • 10252
    • Tampa Bay Buccaneers
    • +1250
  • Oct 05

    12:00 PM

    • 10253
    • Arizona Cardinals
    • +3500
    • 10254
    • Los Angeles Rams
    • -167
    • 10255
    • San Francisco 49ers
    • +470
    • 10256
    • Seattle Seahawks
    • +295

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