2025 Thursday Night Football Best Bets - NFL Lines & Picks

2025 NFL Thursday Night Football Week 2 Betting Lines

NFL Thursday Night Football Betting

A battle between NFC playoff teams from a season ago gets the Week 2 NFL betting schedule underway. The Washington Commanders surprised a lot of folks winning 12 games and reaching the NFC Championship. The team formerly known as the Redskins hadn’t won that many games since the 1991 season. This year might be more challenging since opponents won’t be snuck up on, but Jayden Daniels is the real deal winning NFL Offensive Rookie of the Year. The Commanders face the Green Bay Packers at Lambeau Field at 8:15 p.m. ET.

The acquisition of Micah Parsons turned a lot of attention toward the Packers. After the trade Green Bay moved to the favorite in the NFC North and saw their Super Bowl odds shrink. Green Bay ranked among the top 10 in points and total yards on both offense and defense last season and they’re hopeful Parsons can be a difference maker. Green Bay is an early 1.5-point favorite on the NFL betting line. With both teams expected to be in the playoff hunt at seasons the result of this game could play a role in seeding. This will be the first meeting between the clubs since the 2022 season.

Packers vs. Commanders TNF Week 2 Lines

Spread: Packers -3

Total: 48

Money Line: Packers -182 / Commanders  +156

The teams first played back in 1932 but there isn’t a lot of history between them, at least on the field. The biggest connection between the two is the guy who has his name on the NFL’s championship trophy. After leading the Packers to three NFL championships and two Super Bowl wins, Vince Lombardi coached Washington for one season. It wasn’t a spectacular year, but the club went 7-5-2 for its first winning season in 14 years.

Looking to build off their successful 2024 campaign, the Commanders opened the season with an impressive win over the Giants. Daniels picked up where he left off last season throwing for 233 yards and a touchdown while adding 68 yards on 11 rush attempts. Last year the Commanders were seventh in the league averaging 369.6 yards but ranked just 17th in passing. The evolution of Daniels and the acquisition of Deebo Samuel should help improve that area. Samuel was targeted 10 times against the Giants making seven catches for 77 yards. He added a 19-yard TD run in the fourth quarter on his only carry to put the game away.

The Commanders amassed 432 yards and averaged 6.6 yards per play, but it was the defense that came up big. In their final game of the 2024 season, the unit allowed 459 yards and 55 points to the Eagles in the NFC Championship. On Sunday they held Russell Wilson to 17 of 37 passing and 168 yards while limiting the Giants to 231 total yards and no touchdowns.

The addition of Parsons will help Green Bay’s defense. The former Defensive Rookie of the Year had at least 12 sacks in each of his first four seasons in the league. That’s an area the Packers haven’t had a lot success in. The last Green Bay defender to record more than 10 sacks in a season was Za’Darius Smith with 12.5 in 2020.

Few players are still around from when the teams last met in Week 7 of the 2022 season. Washington QB Taylor Heinicke tossed a pair of TD passes in a 23-21 victory that ended a two-game losing streak. We’ve seen a lot of roster turnover in the years since largely because both teams missed the playoffs that season. The Packers have won the last four games played between the teams in Green Bay with three payouts. Three of those games.

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2025 Thursday Night Football Schedule

WEEK VISITING TEAM HOST TEAM SCORE
Week 1 Dallas Cowboys Philadelphia Eagles 20-24
Week 2 Washington Commanders Green Bay Packers -
Week 3 Miami Dolphins Buffalo Bills -
Week 4 Seattle Seahawks Arizona Cardinals -
Week 5 San Francisco 49ers Los Angeles Rams -
Week 6 Philadelphia Eagles New York Giants -
Week 7 Pittsburgh Steelers Cincinnati Bengals -
Week 8 Minnesota Vikings Los Angeles Chargers -
Week 9 Baltimore Ravens Miami Dolphins -
Week 10 Las Vegas Raiders Denver Broncos -
Week 11 New York Jets New England Patriots -
Week 12 Buffalo Bills Houston Texans -
Week 13 Chicago Bears Philadelphia Eagles -
Week 14 Dallas Cowboys Detroit Lions -
Week 15 Atlanta Falcons Tampa Bay Buccaneers -
Week 16 Los Angeles Rams Seattle Seahawks -
Week 17 Denver Broncos Kansas City Chiefs -
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