The UEFA Champions League 2025/26 Round of 16 (last 16) is the first knockout round after the league phase and play-offs, featuring 16 elite teams in high-stakes two-legged ties. The draw took place on February 27, 2026, in Nyon, Switzerland, setting up some blockbuster matchups—including rematches of recent classics like Real Madrid vs. Manchester City (fifth straight year in the knockouts) and PSG vs. Chelsea (with revenge angles from last summer's Club World Cup final).
This stage uses a fixed bracket: unseeded teams (those who came through the playoffs or lower league-phase finishes) host the first legs, while seeded teams (the top 8 from the league phase) get home advantage in the second legs. The aggregate winner of each tie advances to the quarter-finals (April 7/8 & 14/15, 2026).
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UEFA CL Round of 16 First Leg Schedule and Odds at Bookmaker
All Times Eastern - All Games Televised on Paramount+
Galatasaray vs Liverpool
Date: Tuesday, March 10, 2026
Kick-off Time: 1:45 PM
Venue: RAMS Park (Ali Sami Yen Spor Kompleksi), Istanbul, Türkiye
Odds: Galatasaray +300, Draw +300, Liverpool -135. Over 2.5 Goals -192, Under 2.5 Goals +148
Galatasaray qualified for the knockout stage after beating Juventus 7-5 on aggregate in the play-off round.
Liverpool finished 3rd in the Champions League phase, earning a direct path to the round of 16.
Atalanta vs. Bayern Munich
Date: Tuesday, March 10, 2026
Kick-off Time: 4:00 PM
Venue: New Balance Arena, Bergamo, Italy
Odds: Atalanta +380, Draw +340, Bayern Munich -170. Over 2.5 Goals -230, Under 2.5 Goals +176
Atalanta qualified dramatically after a stunning comeback in the play-off round, overturning a deficit against Borussia Dortmund (notably a 4-1 second-leg win featuring red cards and a late penalty).
Bayern Munich earned a direct spot in the round of 16 after a strong league phase (second-best record with 7 wins and 1 defeat). They're heavy favorites overall, led by stars like Harry Kane.
Newcastle United vs. Barcelona
Date: Tuesday, March 10, 2026
Kick-off Time: 4:00 PM
Venue: St. James' Park, Newcastle upon Tyne, England
Odds: New Castle United +180, Draw +280, Barcelona +130. Over 2.5 Goals -205, Under 2.5 Goals +158
Newcastle United advanced through the knockout play-off round with a strong performance (including a 3-2 second-leg win over Qarabag).
Barcelona finished higher in the league phase (around 5th position) to earn a seeded spot in the round of 16.
Atletico Madrid vs. Tottenham Hotspur
Date: Tuesday, March 10, 2026
Kick-off Time: 4:00 PM
Venue: Riyadh Air Metropolitano, Madrid, Spain
Odds: Atletico Madrid -165, Draw +290, Tottenham +410. Over 2.5 Goals -138, Under 2.5 Goals +108
Atletico Madrid advanced to the round of 16 after a convincing knockout play-off victory over Club Brugge (7-4 aggregate, including a 4-1 second-leg win).
Tottenham Hotspur finished 4th in the Champions League phase to earn a direct spot in the round of 16.
Bayer Leverkusen vs. Arsenal
Date: Wednesday, March 11, 2026
Kick-off Time: 1:45 PM
Venue: Bay Arena, Leverkusen, Germany
Odds: Bayer Leverkusen +500, Draw +310, Arsenal -180. Over 2.5 Goals -118, Under 2.5 Goals -102
Bayer Leverkusen finished 16th in the league phase but advanced via the knockout play-off round with a 2-0 aggregate win over Olympiacos.
Arsenal topped the Champions League phase with a perfect record—the only team to do so—earning a seeded spot and a favorable path.
PSG v s. Chelsea
Date: Wednesday, March 11, 2026
Kick-off Time: 4:00 PM
Venue: Parc des Princes, Paris, France
Odds: PSG -130, Draw +300, Chelsea +320. Over 2.5 Goals -174, Under 2.5 Goals +142
As reigning European champions, PSG advanced through the knockout play-off round with a narrow 5-4 aggregate win over Monaco.
Chelsea finished 6th in the Champions League group stage to earn a direct-seeded spot in the round of 16 (secured with a key 3-2 win at Napoli).
Real Madrid vs. Manchester City
Date: Wednesday, March 11, 2026
Kick-off Time: 4:00 PM
Venue: Estadio Santiago Bernabéu, Madrid, Spain
Odds: Real Madrid +175, Draw +260, Manchester City +145. Over 2.5 Goals -174, Under 2.5 Goals +142
Real Madrid advanced via the knockout play-off round with a 3-1 second-leg win over Benfica (aggregate victory after a tight series). They are known as perennial UCL powerhouses (15-time winners).
Manchester City finished in the top eight of the league phase to earn a seeded direct spot in the round of 16. Pep Guardiola's side is in strong contention, having beaten Real Madrid in their league-phase meeting earlier this season.
Bodo Glimt vs. Sporting CP
Date: Wednesday, March 11, 2026
Kick-off Time: 4:00 PM
Venue: Aspmyra Stadion, Bodo, Norway
Odds: Bodo Glimt +165, Draw +260, Sporting CP +150. Over 2.5 Goals -174, Under 2.5 Goals +142
Bodo/Glimt has been the Cinderella story of the competition, advancing dramatically through the knockout play-off round.
Sporting CP finished higher in the league phase (around 7th in some stats) to earn a seeded spot in the round of 16.
UEFA Champions League Round of 16 First LegBest Bets
Main Pick: Liverpool, Bayern Munich, Barcelona, Atletico Madrid, Arsenal, PSG
Over/Under Pick: Bodo/Glimt Over the Total
Player Prop Pick: Harry Kane Over the Scoring Totals
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