At the start of the season, the Philadelphia Eagles and Detroit Lions dominated much of the NFC futures market.
So far, both teams are in the hunt and in the black with the NFL betting odds.
The Lions had to replace both coordinators after their 2024 playoff flop. But head coach Dan Campbell has proven to be the perfect fit in the Motor City to maintain standards.
The Eagles have become the NFL's most innovative, adaptive, and model franchise.
The NFC is loaded with quality teams and legitimate contenders, so losses are not an option for anyone.
This NFC power matchup between the Eagles and Lions could be a playoff preview.
Additionally, the NBC Sunday Night Football brand makes for a certain stampede at the betting window.
Get the latest NFL Week 11 news, check out the current betting lines for the games, and don’t miss Sunday Night Football action, all with the best odds at BookMaker!
Detroit Lions at Philadelphia Eagles Odds at Bookmaker
Lincoln Financial Field is the venue for the matchup between the Philadelphia Eagles and the Detroit Lions on Sunday, November 16, 2025. Kickoff time is at 8:20 p.m. ET with television coverage on NBC.
Oddsmakers opened with Philadelphia as a 1.5-point favorite and Detroit as a 1.5-point dog.
Philadelphia is a -128 moneyline favorite with Detroit as a +106 moneyline dog.
Philadelphia and Detroit opened with a total of 48.5.
Detroit Lions
Last game, the Detroit Lions won 44-22 against the Washington Commanders as 8.5-point road favorites. The game went over the total of 48.5.
Detroit is 6-3 straight up, 6-3 against the spread, and 5-4 over/under the total.
Detroit ranks 6th for total offense, 11th for passing, 6th for rushing, 2nd for scoring, and 5th for fewest turnovers committed.
Detroit ranks 7th in total defense, 13th vs. the pass, 8th vs. the rush, 12th in fewest points allowed, and 8th in takeaways.
Detroit is tied with the Green Bay Packers for the NFC North lead.
The Lions hold the 3-seed for the 2025 NFC Playoffs.
Philadelphia Eagles
Last game, the Philadelphia Eagles won 10-7 against the Green Bay Packers as 1-point road favorites. The game went under the total of 44.5.
Philadelphia is 7-2 straight up, 6-3 against the spread, and 5-4 over/under the total.
Overall, Philadelphia ranks 23rd for total offense, 25th for passing, 21st for rushing, 12th for scoring, and 1st for fewest turnovers committed.
Philadelphia ranks 18th for total defense, 14th vs. the pass, 19th vs. the rush, 10th for fewest points allowed, and 21st for takeaways.
Philadelphia leads the NFC East Division by 3.5 games over the Dallas Cowboys.
The Eagles are tied with the Seattle Seahawks for the top seed in the NFC Playoffs.
Lions at Eagles Betting Trends
The Lions have been bank as a road team lately.
Detroit covered the spread in 15 of its last 20 away games.
Detroit went over the total in four of its most recent six away tilts.
Meanwhile, the Eagles have been a good investment at Lincoln Financial Field.
Philadelphia covered the spread in eight of its most recent 11 games.
Philadelphia went over the total in five of its last seven home games.
In the series between the Eagles and Lions, Detroit has bossed the payout window.
The Lions covered the spread in six of their last eight games with the Eagles.
The Eagles and Lions went over the total in nine consecutive games.
Specifically in Philadelphia, the Lions came away with the cash in two of their last three visits against the Eagles.
The last four meetings between the Lions and Eagles at Philadelphia went over the total.
Lions at Eagles Best Bets
The Lions and Eagles have become two of the most popular teams on the board.
Detroit will get plenty of looks from sharps and bargain hunters as an elite road team.
Philadelphia will get its share of casual support as the power home team.
The price should be honest and balanced, as the oddsmakers know betting action will be heavy on both sides.
In this situation, Detroit is the better value as the power road dog.
As mentioned earlier, the Lions have no problem getting the cash vs. the Eagles.
Main Pick: Detroit Lions
Over/Under Pick: Over the Total
Player Prop Picks: Jalen Hurts Under the Total Yards Total
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