
Once upon a time, NFL teams did not want to play on Thanksgiving Day. Although that was the case, the NFL begged for volunteers. The Detroit Lions volunteered and have hosted one of the Turkey Day games ever since.
One of the most famous of those Thanksgiving Day games in Detroit occurred in 1962, when the Lions ambushed and routed the undefeated, eventual NFL champion Green Bay Packers.
On Thursday, the tradition is renewed as the Packers visit the Lions in a key matchup with playoff implications. In fact, it is one of the most impactful matchups of the season.
Packers, Lions, Thanksgiving. Nothing epitomizes the Great American Holiday and historic rivalry pro football action more than this one. Betting action will be a continuous stampede.
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Green Bay Packers at Detroit Lions Odds at Bookmaker
Ford Field is the venue for the matchup between the Green Bay Packers and the Detroit Lions on Thursday, November 27, 2025. Kickoff time is at 1 p.m. ET with television coverage on FOX.
Oddsmakers opened with Detroit as a 3-point favorite and Green Bay as a 3-point dog.
Detroit is a -164 moneyline favorite with Green Bay as a +138 moneyline dog.
Detroit and Green Bay opened with a total of 49.5.
Green Bay Packers
Last game, the Green Bay Packers won 23-6 against the Minnesota Vikings as 6.5-point home favorites. The game went under the total of 41.5.
Green Bay is 7-3-1 straight up, 4-7 against the spread, and 4-6-1 over/under the total.
Green Bay ranks 6th for total offense, 8th for passing, 9th for rushing, 13th for scoring, and 2nd for fewest turnovers committed.
Green Bay ranks 8th for total defense, 9th vs. the pass, 15th vs. the rush, 6th for fewest points allowed, and 22nd for takeaways.
Green Bay has covered one out of its most recent four games. Green Bay went under the total in three of its last four matchups.

Detroit Lions
Last game, the Detroit Lions won 34-27 against the New York Giants in overtime as 14-point home favorites. The game went over the total of 50.5.
Detroit is 7-4 straight up, 6-5 against the spread, and 6-5 over/under the total.
Overall, Detroit ranks 4th for total offense, 9th for passing, 3rd for rushing, 2nd for scoring, and 3rd for fewest turnovers committed.
Detroit ranks 10th for total defense, 15th vs. the pass, 9th vs. the rush, 11th for fewest points allowed, and 9th for takeaways.
Detroit has covered one out of its most recent four games. Detroit went over the total in three of its last four matchups.
Packers at Lions Betting Trends
Green Bay covered the spread in only one of their last seven road tilts.
The Packers went over the total in 14 of their last 20 away games.
The Lions have cashed in four of their most recent six home games.
Detroit went over the total in 13 of its last 20 games at Ford Field.
In the series between the Packers and Lions, Detroit covered 12 of the most recent 17 meetings.
Green Bay got the money in three of the most recent four games.
The Packers and Lions went over the total in 12 of their last 20 matchups.
Specifically in Detroit, the Lions covered the spread in six of their most recent eight home games against the Packers.
The Pack paid in its two most recent visits.
Three of the last four games between the Packers and Lions at Detroit went over the total.
Packers at Lions Best Bets
The Lions' Thanksgiving home game has long been a popular pick among casual fans.
Now that Detroit is actually a good team and a serious contender, the appeal to squares will be more pronounced.
Detroit has become a favorite team in the gambling community. Especially when playing at home, the Lions draw significant betting traffic.
Similarly, the Packers brand is among the most popular on the board.
Green Bay has the credibility with gamblers as a perennial contender for nearly three decades.
Wise Guys love a strong road team that combines a more favorable price and quality.
On this occasion, casual-sector funds will flow to the Lions.
The Packers will offer maximum NFL wagering value as the quality away team backed by a majority of sharps.
Main Pick: Green Bay Packers
Over/Under Pick: Over the Total
Player Prop Picks: Jared Goff Under the Passing Yards Total
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