To get Week 6 underway is a Thursday Conference USA matchup between the New Mexico State Aggies and Sam Houston Bearkats.
Sam Houston is struggling as it goes through a painful coaching transition. Offensive wizard Phil Longo is in his first year at the helm and is discovering why his predecessor, KC Keeler, left for Temple.
Meanwhile, New Mexico State is one of the least successful programs in college football history. Previously, Jerry Kill led them to bowl games in 2022 and 2023 before stepping down due to health concerns.
Explore the Week 6 odds and betting action for Thursday Night College Football.
College Football Betting Lines
Sam Houston Bearkats at New Mexico State Aggies Odds at Bookmaker
Aggie Memorial Stadium in Las Cruces, New Mexico, is the venue for the Thursday, October 2, 2025, Conference USA matchup between the host New Mexico State Aggies and the Sam Houston Bearkats. Kickoff time is set for 9 p.m. ET, with television coverage available on CBSSN.
The Sam Houston Bearkats opened as a 2.5-point road favorite with New Mexico State as a 2.5-point home dog.
The Bearkats and Aggies opened with a total of 51.5.
Sam Houston opened as a -142 moneyline favorite with New Mexico State as a +118 home dog.
Sam Houston Bearkats
In their last game, the Sam Houston Bearkats lost 55-0 to the Texas Longhorns. The game went under the total of 51.5.
Sam Houston has a record of 0-4 straight up and against the spread and is 3-1 over the total.
Sam Houston State ranks 133rd for total offense, 129th for scoring, but 29th for fewest turnovers committed.
Sam Houston ranks 131st for total defense and 134th for points allowed.
Arch Manning passed for 309 yards and three touchdowns and ran for two more scores to lead the rout of Sam Houston.
Texas dismantled hapless Sam Houston as Manning hit on 18 of his 21 throws and connected with eight different receivers before heading to the bench early in the third quarter.
The Longhorns outgained Sam Houston 607-113 and amassed 10 tackles for a loss, including five sacks.
New Mexico State Aggies
Last week, the New Mexico State Aggies lost 28-20 against the New Mexico Logos as 15.5-point road dogs. The game went over the total of 51.5.
New Mexico State has a record of 2-2 straight up, 1-3 against the spread, and 2-2 over the total.
New Mexico State has national metrics of 126th for total offense, 120th for scoring offense, and 94th for fewest turnovers committed.
The Aggies rank 114th for total defense and 84th for fewest points allowed.
Sam Houston at New Mexico State Betting Trends
Late on, the Sam Houston Bearkats failed to cover the spread in seven of their most recent eight away games.
Five of Sam Houston’s last eight away games went over the total.
New Mexico State got the cash in 13 of its most recent 19 home games.
The Aggies went under the total in only two of their last seven games at home.
Previously in this series, each team had a win and a cover. In each game, the home team won and got the money.
Both games went under the total.
Sam Houston at New Mexico State Best Bets
As mentioned earlier, this is a home team series.
Sam Houston struggles on the road, while New Mexico State has been a good value at home.
Main Pick: New Mexico State Aggies
Over/Under Pick: Over the Total
Player Prop Picks: Logan Fife Over the Passing Yards Total
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