Two of the greatest historic brands in college basketball will clash on Saturday.
The Michigan State Spartans have started strong as legendary head coach Tom Izzo continues to defy the critics.
Similarly, the Duke Blue Devils look like Final Four material after their run last year.
Duke head coach Jon Sheyer has proven to be the perfect choice to replace Mike Krzyzewski.
Scheyer has made Duke one of the most popular brands on the college basketball betting board.
Both teams are elite defensively. However, Duke has a vastly superior offense compared to MSU.
With two of the biggest brands in college basketball matching up on Saturday at High Noon on FOX, betting activity will be over the top.
Get the latest College Basketball news, check out the current betting lines for the games, and don’t miss the basketball action, all with the best odds at BookMaker!
Duke Blue Devils at Michigan State Spartans Betting at Bookmaker
The Breslin Center in East Lansing, MI, hosts the matchup between the Duke Blue Devils and the Michigan State Spartans on Saturday, December 6, 2025. Tipoff time is at Noon ET with television coverage on FOX.
Duke will offer maximum value as the power road team opposing a blueblood home team.
Sharps and bargain hunters will like the Blue Devils in this spot.
On the other hand, squares will latch onto the Spartans on their home court.
Duke Blue Devils
The Duke Blue Devils are 9-0 straight up, 6-3 against the spread, and 1-8 over/under the total. Late on, Duke has covered one out of their last three games. At the same time, the Blue Devils have gone under the total in one of their previous five matchups.
Duke has NCAABB metrics of 67th in scoring offense, 23rd in field goal percentage, 101st in 3-point field goal percentage, 177th in free throw percentage, and 60th in offensive rebounding.
Defensively, the Blue Devils rank 5th in scoring defense, 2nd in field goal percentage permitted, 14th in 3-point field goal percentage allowed, and 67th in defensive rebounding.
Michigan State Spartans
The Michigan State Spartans are 8-0 straight up, 5-3 against the spread, and 2-6 over/under the total. Late on Michigan State, they have covered four of their last five games. At the same time, the Spartans have gone under the total in one of their previous six matchups.
Michigan State has NCAABB metrics of 293rd in scoring offense, 105th in field goal percentage, 202nd in 3-point field goal percentage, 142nd in free throw percentage, and 70th in offensive rebounding.
Defensively, the Spartans rank 7th in scoring defense, 29th in field goal percentage allowed, 42nd in 3-point field goal percentage allowed, and 4th in defensive rebounding.
Duke at Michigan State Betting Trends
Duke has been an exceptional betting value on the road.
The Blue Devils lost only four of their most recent 20 away games.
Duke went over the total in six of their last nine away tilts.
Michigan State has recently seen a drop in value at the Breslin Center.
The Spartans failed to cover three of their last four home games.
Michigan State went under the total in 14 of their most recent 17 home matchups.
Duke has had the advantage in their series with Michigan State.
The Blue Devils got the money in seven of their last ten games against the Spartans.
Six of the last nine games between Duke and Michigan State went over the total.
Duke won and covered the spread in both of their previous two away games against Michigan State. The games were 1-1 on the over/under.
Duke at Michigan State Bookmaker Best Bets
In this matchup, Duke has a distinct offensive advantage against Michigan State.
The plodding Spartan offense will have them playing catch-up against one of the best defenses in the land.
Most importantly, Duke will offer a better price as the road team.
Main Pick: Duke Blue Devils
Over/Under Pick: Under the Total
Player Prop Picks: Cameron Boozer Over the Points Total
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