2025 St. Louis Cardinals Betting Lines - MLB Odds

St. Louis Cardinals 2025 MLB Betting Lines

St. Louis Cardinals Betting Lines

Following two years in the playoff wilderness, the 2025 St. Louis Cardinals are in the thick of the postseason race. St. Louis spent the past two years retooling their roster, and management moves are finally paying dividends. Most importantly, the Cardinals are one of the biggest moneymakers on the 2025 MLB board. Last year, the Cardinals were unable to make up enough ground to make the playoffs, as an aging team in transition. After going 93-69 and winning the National League Central in 2022, the St. Louis Cardinals fell to 71-91 in 2023. The Cardinals fired Mike Shildt after the 2021 season, despite the fact that Shildt had never had a losing record and had produced three playoff campaigns in his final three seasons. Shildt’s replacement, Oliver Marmol, was the man who presided over the collapse. Marmol was feeling serious heat on Opening Day this season, but is now looking like an asset.

MLB Betting Lines

St. Louis Cardinals MLB Betting Lines

The St. Louis Cardinals are +7000 to win the 2025 World Series, +3500 to win the National League Pennant, and +500 to win the National League Central. St. Louis ranks 12th for MLB payroll.

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Halfway Report

The St. Louis Cardinals are 47-38 and 44-38-3 under the total. The Cardinals are third in the National League Central, 2.5 games behind the Chicago Cubs. St. Louis is 26-17 at home and is 21-21 on the road. St. Louis is +820 units with the moneyline and +472 for the run line. The Cardinals are +764 units at home and +56 on the road.

The Cardinals rank 7th for run production, 12th for OPS, and 17th for home runs. On the mound, St. Louis ranks 16th for earned run average, 14th for WHIP, 8th for quality starts, 15th for bullpen earned run average, and 5th for the fewest errors committed.

Key Players

RHP Sonny Gray is the Cardinals' number-one starter. In 2023, Gray was 8-8 with a 2.79 ERA and 1.15 WHIP. Last year, Gray was 13-9 with a 3.84 ERA and 1.09 WHIP. Gray is a 3-time All-Star. So far in 2025, Gray is 8-2 with a 3.36 earned run average and 1.09 WHIP.

Closer Ryan Helsley is 4-2 with a 3.41 earned run average and a 1.41 WHIP. He has 16 saves in 21 opportunities. Last year, Helsley compiled 49 saves in 53 opportunities. He was a National League All-Star in 2022 and 2024.

Designated hitter Alec Burleson leads the Cardinals with 27 runs, 13 doubles, 10 home runs, 37 runs batted in, a .298 batting average, and .804 OPS. Burleson began his career with the Cardinals in 2022 and hit 21 home runs last year.

Second baseman Brendan Donovan has 45 runs, 21 doubles, six home runs, 31 runs batted in, a .297 batting average, and a .793 OPS.

Manager

Since 2022, Oliver Marmol has been the manager of the Cardinals. He led St. Louis to a Central Division title in 2022.

Season-by-Season Record (Since 2015)

SEASON WINS LOSSES FINISH POSTSEASON
2024 83 79 2nd -
2023 71 91 5th -
2022 93 69 1st Lost NLWC (Phillies) 2–0
2021 90 72 2nd Lost NLWC (Dodgers) 1–0
2020 30 28 2nd Lost NLWC (Padres) 2–1
2019 91 71 1st Lost NLCS (Nationals) 4–0
2018 88 74 3rd -
2017 83 79 3rd -
2016 86 76 2nd -
2015 100 62 1st Lost NLDS (Cubs) 3–1
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